Protein Alignment Tsp42Ea and TSPAN7

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_004606.2
• Gene: TSPAN7 / 7102
• HGNCID: 11854
• Length: 249
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 64/235 - (27%)
• Similarity: 109/235 - (46%)
• Gaps: 27/235 - (11%)

  Fly     5 ISMVKYILFIFNLLCSICGILLI---VFGALLFSKVRNMDDFAEALRTQQVPVTMIILGTIILLI 66
            |:.:|.:|.|::.:..|.|::|:   |:|.|......::  .||  .:...|..:|..||.|::.
Human    12 ITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISL--IAE--NSTNAPYVLIGTGTTIVVF 72

  Fly    67 SWFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWV----QKDKYLEIMGDVVEKAWNHRTS 127
            ..|||....|.|..|...|::.|.::.:.:|...|..:|    .||.:|....|.:: .:|....
Human    73 GLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQ-TYNGNDE 136

  Fly   128 RSDYMDAIQISMKCCGRSGYTDYAYQGKF-----PPSCCSDTNNCRWETVY----------RRGC 177
            ||..:|.:|.|:.|||...||:::....|     |||||.:..:|..:.::          ::||
Human   137 RSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETDCNPQDLHNLTVAATKVNQKGC 201

  Fly   178 KVTFVEFWDRNSDIIKYAGLVIAAIEFVGFVFACCLANSI 217
            ......|.:.|..||......||..:.:|.:.||||:..|
Human   202 YDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFI 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	62/228 (27%)
TSPAN7	NP_004606.2	Tetraspanin	15..239	CDD:459767	62/228 (27%)
		TM4SF2_6_like_LEL	110..213	CDD:239414	26/103 (25%)