Protein Alignment Tsp42Ea and Tspan1

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_598442.1
• Gene: Tspan1 / 66805
• MGIID: 1914055
• Length: 240
• Species: Mus musculus
• Alignment Length: 249
• Identity: 60/249 - (24%)
• Similarity: 111/249 - (44%)
• Gaps: 50/249 - (20%)

  Fly     1 MSCGISMVKYILFIFNLLCSICGILLI---------------VFGALLFSKVRNMDDFAEALRTQ 50
            |.| ...:|.::|:||||..:||..|:               |||:|..|          |::..
Mouse     1 MQC-FKFIKVMMFLFNLLIFLCGAALLAVGIWVSVDGTSFLKVFGSLSSS----------AMQFV 54

  Fly    51 QVPVTMIILGTIILLISWFGCCGAIRESYCMSMTYSILLFVLMIGQLA----LVIYMWVQKDKYL 111
            .|...:|..|.::.::.:.||.||..|:.|:.|.:..:|.::.|.::|    .::|..:.:....
Mouse    55 NVGYFLIAAGAVLFILGFLGCYGAHSENKCVLMMFFSILLIIFIAEIAGAVVALVYTTLAEQFLT 119

  Fly   112 EIMGDVVEKAWNHRTSRSDYMDAIQISMKCCGRSGYTD-----YAYQGK-FPPSCCSDTNN---- 166
            .::...:||.:.::|..:...:.....:.|||.:.|||     :..:.| |||.||::..|
Mouse   120 LLVVPAIEKDYGYQTDFTQVWNTTMEELHCCGFNNYTDFNASRFVKENKVFPPPCCANPGNHTVE 184

  Fly   167 -CRWE---TVYRRGCKVTFVEFWDR-NSDIIKYAGLV--IAAIEFVGFVFACCL 213
             |..|   ::..:||   |.|...| .::.:...|:.  :||:|....|.:..|
Mouse   185 PCTEEKAKSMKVQGC---FKEILHRIRANAVTVGGVAVGVAALELAAMVVSMYL 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	58/242 (24%)
Tspan1	NP_598442.1	Tetraspanin	7..>151	CDD:459767	33/153 (22%)
		uroplakin_I_like_LEL	106..208	CDD:239409	24/104 (23%)