Protein Alignment Tsp42Ea and tspan33b

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: XP_005159085.1
• Gene: tspan33b / 567512
• ZFINID: ZDB-GENE-060503-607
• Length: 266
• Species: Danio rerio
• Alignment Length: 252
• Identity: 60/252 - (23%)
• Similarity: 114/252 - (45%)
• Gaps: 47/252 - (18%)

  Fly     8 VKYILFIFNLLCSICGILLIVFGALLFSKVRNMDDFAEALRTQQVPVTMIILGTIILLISWFGCC 72
            ::|.||.|:.|..:..:|::..|  :::|.:...|...........|.:|::|.::..|::.||.
Zfish    20 IRYFLFFFSFLFWVFSLLIVAIG--VYAKAQKATDTVRDSFLIDPAVILIVVGVVMFFITFCGCI 82

  Fly    73 GAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMGDVVEKAWNHRTSRSD---YMDA 134
            ||:||:..:...:|..|.::.:.|:|:.|..:...::..:.:|:.|:||..|.....|   .||.
Zfish    83 GALRENIRLLKIFSFSLTLVFLTQMAIAILGFFYSEQTRDALGEFVKKAIVHYRDDLDLQNLMDY 147

  Fly   135 IQISMKCCGRSGYTDYAYQGKF--------------PPSCCSD-------TNNCRW--------- 169
            ||...||||.:.|||:::...|              |.|||:.       .:.|.:
Zfish   148 IQKEFKCCGWTNYTDWSWNPYFNCSSSNPSNERCSVPFSCCTPLPRETVINSMCGFGIQTQNHLN 212

  Fly   170 --ETVYRRGC---KVTFVEFWDRNSDIIKYAGLV--IAAIEFVGFVFACCLANSIRN 219
              :::|..||   .|.::|     |.::.:..|.  :|..:..|.|.:..|.:.||:
Zfish   213 ATKSIYSVGCADRAVIWIE-----SHLLLFGALTLGLALPQIAGIVLSQILISEIRS 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	58/246 (24%)
tspan33b	XP_005159085.1	Tetraspanin	36..>156	CDD:459767	31/121 (26%)
		penumbra_like_LEL	114..234	CDD:239411	29/124 (23%)