Protein Alignment Tsp42Ea and Tspan6

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_062630.2
• Gene: Tspan6 / 56496
• MGIID: 1926264
• Length: 245
• Species: Mus musculus
• Alignment Length: 230
• Identity: 59/230 - (25%)
• Similarity: 105/230 - (45%)
• Gaps: 19/230 - (8%)

  Fly     5 ISMVKYILFIFNLLCSICGILLIVFGALLFSKVRNMDDFAEAL--RTQQVPVTMIILGTIILLIS 67
            |:.:|.:|.|:..:..|.|::|:..|  ::.|| :::::...|  :...||..:|..||:|:|:.
Mouse    14 ITCLKSVLLIYTFIFWITGVILLAVG--IWGKV-SLENYFSLLNEKATNVPFVLIGTGTVIILLG 75

  Fly    68 WFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMGDVVEKAWNHRTSRSDY- 131
            .|||....|.|..|...|::.|.::.:.:|...|..:|.:.:.........|.|.....|..||
Mouse    76 TFGCFATCRASAWMLKLYAMFLTLIFLVELVAAIVGFVFRHEIKNSFKSNYENALKEYNSTGDYR 140

  Fly   132 ---MDAIQISMKCCGRSGY-----TDYAYQGKFPPSCCSDTNNC----RWETVYRRGCKVTFVEF 184
               :|.||.::.|||.:.|     |:|..:..||.|||. ...|    ..:.|...||.:..:..
Mouse   141 SEAVDKIQSTLHCCGVTNYGDWKGTNYYSETGFPKSCCK-LEGCYPQRDADKVNEEGCFIKVMTT 204

  Fly   185 WDRNSDIIKYAGLVIAAIEFVGFVFACCLANSIRN 219
            .:....::......:|..:.:|...|.||:.:|.|
Mouse   205 IESEMGVVAGISFGVACFQLIGIFLAYCLSRAITN 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	56/221 (25%)
Tspan6	NP_062630.2	Tetraspanin	17..235	CDD:459767	56/221 (25%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	24/97 (25%)