Protein Alignment Tsp42Ea and TSPAN11

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: XP_011518981.1
• Gene: TSPAN11 / 441631
• HGNCID: 30795
• Length: 302
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 53/237 - (22%)
• Similarity: 97/237 - (40%)
• Gaps: 39/237 - (16%)

  Fly     5 ISMVKYILFIFNLLCSICGILLIVFGA-LLFSKVRNMDDFAEALRTQQVPVTMIILGTIILLISW 68
            |..:||:||:||....:.|..::..|. .|..|...:...|.:  |......::|...::::::.
Human    13 IIYLKYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASS--TFAASAYILIFAGVLVMVTG 75

  Fly    69 FGCCGAI--RESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMGDVVEKAWNHRTSRSDY 131
            |...|||  ....|:| ||..||.|:.:.:|...:...|    |.:.:.|.:::..| ||...:|
Human    76 FLGFGAILWERKGCLS-TYFCLLLVIFLVELVAGVLAHV----YYQRLSDELKQHLN-RTLAENY 134

  Fly   132 -----------MDAIQISMKCCGRSGYTDYAY---------QGK-FPPSCCSDT-----NNCRWE 170
                       :|.:|...||||.:...|:.:         :|: .|.|||...     ......
Human   135 GQPGATQITASVDRLQQDFKCCGSNSSADWQHSTYILLREAEGRQVPDSCCKTVVVRCGQRAHPS 199

  Fly   171 TVYR--RGCKVTFVEFWDRNSDIIKYAGLVIAAIEFVGFVFA 210
            .:|:  .||.....:|...:..::...|:.:|.::....|.|
Human   200 NIYKVEGGCLTKLEQFLADHLLLMGAVGIGVACLQITEDVIA 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	52/234 (22%)
TSPAN11	XP_011518981.1	Tetraspanin	16..>158	CDD:459767	37/149 (25%)
		CD151_like_LEL	112..220	CDD:239408	23/112 (21%)