Protein Alignment Tsp42Ea and CD82

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: XP_047282856.1
• Gene: CD82 / 3732
• HGNCID: 6210
• Length: 308
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 72/270 - (26%)
• Similarity: 117/270 - (43%)
• Gaps: 50/270 - (18%)

  Fly     2 SCGISMVKYILFIFNLLCSICGILLIVFGALLFSKVRNMDDFAEALRTQQVPVTM-----IILGT 61
            |..|.:.||.||:|||:..|.|.:::.||..:.:   :...|...|:|....:.|     |.:|.
Human    44 SACIKVTKYFLFLFNLIFFILGAVILGFGVWILA---DKSSFISVLQTSSSSLRMGAYVFIGVGA 105

  Fly    62 IILLISWFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMGDVV-EKAWNHR 125
            :.:|:.:.||.||:.|..|:...|...|.:::|.|:......:....|..:.||.:| |...::.
Human   106 VTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTELIRDYN 170

  Fly   126 TSRSDYM----DAIQISMKCCGRSGY---TDYAY-----QGKFPPSC----------------CS 162
            :||.|.:    |.:|..:||||...:   ||.|.     :..:|.||                |.
Human   171 SSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEEDNSLSVRKGFCE 235

  Fly   163 DTNNCR--------WETVYRRGCKVTFVEFW-DRNSDIIKYAGLVIAAIEFVGFVFACCLANSI- 217
            ...|..        | .||:.|| :..|:.| ..|..||...|:.:|.||.:|.|.:.||...:
Human   236 APGNRTQSGNHPEDW-PVYQEGC-MEKVQAWLQENLGIILGVGVGVAIIELLGMVLSICLCRHVH 298

  Fly   218 -RNYRRRAEY 226
             .:|.:..:|
Human   299 SEDYSKVPKY 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	68/249 (27%)
CD82	XP_047282856.1	Tetraspanin	65..295	CDD:459767	60/234 (26%)
		CD37_CD82_like_LEL	147..270	CDD:239413	30/124 (24%)