Protein Alignment Tsp42Ea and Tspan7

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_001385666.1
• Gene: Tspan7 / 363447
• RGDID: 1589725
• Length: 249
• Species: Rattus norvegicus
• Alignment Length: 235
• Identity: 65/235 - (27%)
• Similarity: 107/235 - (45%)
• Gaps: 27/235 - (11%)

  Fly     5 ISMVKYILFIFNLLCSICGILLI---VFGALLFSKVRNMDDFAEALRTQQVPVTMIILGTIILLI 66
            |:.:|.:|.|::.:..|.|.:|:   |:|.|......::  .||  .:...|..:|..||.|::.
  Rat    12 ITCLKTLLIIYSFVFWITGAILLAVGVWGKLTLGTYISL--IAE--NSTNAPYVLIGTGTTIVVF 72

  Fly    67 SWFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWV----QKDKYLEIMGDVVEKAWNHRTS 127
            ..|||....|.|..|...|::.|.::.:.:|...|..:|    .||.:|....|.::. :|.:..
  Rat    73 GLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQN-YNGKDE 136

  Fly   128 RSDYMDAIQISMKCCGRSGYTDYAYQGKF-----PPSCCSDTNNCR----------WETVYRRGC 177
            ||..:|.:|.|:.|||...||:::....|     |||||.:..:|.          ...|.::||
  Rat   137 RSRAVDHVQRSLSCCGVQNYTNWSSSPYFLEHGIPPSCCMNETDCNPLDLHNLTVAATKVNQKGC 201

  Fly   178 KVTFVEFWDRNSDIIKYAGLVIAAIEFVGFVFACCLANSI 217
            ......|.:.|..||......||..:.:|.:.||||:..|
  Rat   202 YDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFI 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	63/228 (28%)
Tspan7	NP_001385666.1	Tetraspanin	15..239	CDD:459767	63/228 (28%)
		TM4SF2_6_like_LEL	110..213	CDD:239414	27/103 (26%)