Protein Alignment Tsp42Ea and TSPAN33

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_848657.1
• Gene: TSPAN33 / 340348
• HGNCID: 28743
• Length: 283
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 62/262 - (23%)
• Similarity: 114/262 - (43%)
• Gaps: 45/262 - (17%)

  Fly     7 MVKYILFIFNLLCSICGILLIVFGALLFSKVRNMDDFAEALRTQQVPVTMIILGTIILLISWFGC 71
            :|||:||.||:|..:..::::..|  :::::....:.|.|.......:.:|::|.::.|:::.||
Human    21 LVKYLLFFFNMLFWVISMVMVAVG--VYARLMKHAEAALACLAVDPAILLIVVGVLMFLLTFCGC 83

  Fly    72 CGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMGDVVEKAWNHRTSRSDYMDAIQ 136
            .|::||:.|:..|:|:.|..:.:.|||..|..:|..||....:.:::..|..|.....|..:.|.
Human    84 IGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDDLDLQNLID 148

  Fly   137 ISMK---CCGRSGYTDYAYQGKF--------------PPSCCSDTNN-------C---------- 167
            ...|   |||...|.|::....|              |.|||..|.:       |
Human   149 FGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAVINTMCGQGMQAFDYL 213

  Fly   168 -RWETVYRRGCKVTFVEFWDRNSDIIKYAGLVIAAIEFVGFVFACCLANSIR--------NYRRR 223
             ..:.:|..||....|.:...|..::....|.:|..:.||.:.:..|.|.|:        |.:.|
Human   214 EASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQILVNQIKDQIKLQLYNQQHR 278

  Fly   224 AE 225
            |:
Human   279 AD 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	57/241 (24%)
TSPAN33	NP_848657.1	Tetraspanin	22..262	CDD:459767	57/241 (24%)
		penumbra_like_LEL	116..236	CDD:239411	24/119 (20%)