Protein Alignment Tsp42Ea and Tspan18

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_001101220.1
• Gene: Tspan18 / 311210
• RGDID: 1560411
• Length: 248
• Species: Rattus norvegicus
• Alignment Length: 256
• Identity: 54/256 - (21%)
• Similarity: 104/256 - (40%)
• Gaps: 55/256 - (21%)

  Fly     5 ISMVKYILFIFNLLCSICGILLIVFGALLFSKVRNMDDFAEALRTQQVPVT----MIILGTIILL 65
            :|.:||::|:||....:.|..|:..|..:   :.:...|.|.:.|..:..|    ::.:|.::.|
  Rat     6 LSCMKYLMFVFNFFVFLGGACLLGVGIWV---LVDPTGFREIVATNPLLTTGAYVVLAMGGLLFL 67

  Fly    66 ISWFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWV----------QKDKYLEIMG----D 116
            :.:.|||||:||:.|:.:.:.:.:.::.:.:|:..|..::          .|:......|    |
  Rat    68 LGFLGCCGAVRENRCLLLFFFLFILIIFLVELSAAILAFIFREHLTREFFTKELTKHYQGDNDTD 132

  Fly   117 VVEKAWNHRTSRSDYMDAIQISMKCCGRSGYTDYAYQGKF----------PPSCCS--------- 162
            |....||          ::.|:..|||.:|..|:.....|          |.:||.
  Rat   133 VFSATWN----------SVMITFGCCGVNGPEDFKLASVFRLLTLDTEEVPKACCRREPQTRDGV 187

  Fly   163 --DTNNC---RWETVYRRGCKVTFVEFWDRNSDIIKYAGLVIAAIEFVGFVFACCLANSIR 218
              ....|   |...:.::||....:..::....:.....:.:.|||....|||.||...|:
  Rat   188 VLSREECQLGRNPFINKQGCYTVILNTFETYVYLAGAFAIGVLAIELFLMVFAMCLFRGIQ 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	52/248 (21%)
Tspan18	NP_001101220.1	Tetraspanin	10..245	CDD:459767	52/247 (21%)
		uroplakin_I_like_LEL	105..218	CDD:239409	20/122 (16%)