Protein Alignment Tsp42Ea and Cd37

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: XP_017444339.1
• Gene: Cd37 / 29185
• RGDID: 62035
• Length: 396
• Species: Rattus norvegicus
• Alignment Length: 280
• Identity: 68/280 - (24%)
• Similarity: 111/280 - (39%)
• Gaps: 72/280 - (25%)

  Fly     2 SCGISMVKYILFIFNLLCSICGILLIVFGA-LLFSKVRNMDDFAEALRTQQVPV-----TMIILG 60
            || :|::||.||:|||...:.|.|:..||. :|..|.    .|...:....||:     .:.:.|
  Rat    29 SC-LSLIKYFLFVFNLFFFVLGGLIFCFGTWILIDKT----SFVSFVGLSFVPLQTWSKVLSVSG 88

  Fly    61 TIILLISWFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLE--IMGDVVEKAWN 123
            .:.:.::..||.||::|..|:...|..:|.:|...|:.|.|.:..|:.: ||  :...|:....:
  Rat    89 VLTMALALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRVR-LERRVQELVLRTIQS 152

  Fly   124 HR-----TSRSDYMDAIQISMKCCGRSGYTDY---------AYQGKFPPSCC---SDTNN----- 166
            :|     |:..:..|..|..::|||.....|:         ..:..|.|..|   :.||:
  Rat   153 YRTNPDETAAEESWDYAQFQLRCCGWQSPRDWNKAQMLKANGSEELFVPCSCYNSTATNDSSGFD 217

  Fly   167 ----------------------CRWET---VYRRGCKVTFVEFWDRNSDIIKYAG--LVIAAIEF 204
                                  |....   :||.|| ...::.|..| :||...|  |.:..:|.
  Rat   218 KLFLSQLSRLGPRAKLRQTADICALPAKAHIYREGC-ARSLQKWLHN-NIISIVGICLGVGLLEV 280

  Fly   205 VGFVFACCLANSIRNYRRRA 224
            .|  .|.||     ..:|||
  Rat   281 SG--MALCL-----QLQRRA 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	62/263 (24%)
Cd37	XP_017444339.1	Tetraspanin	49..>177	CDD:459767	31/132 (23%)
		CD37_CD82_like_LEL	131..266	CDD:239413	24/137 (18%)