Protein Alignment Tsp42Ea and TSPAN17

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_001353420.1
• Gene: TSPAN17 / 26262
• HGNCID: 13594
• Length: 355
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 64/289 - (22%)
• Similarity: 108/289 - (37%)
• Gaps: 93/289 - (32%)

  Fly     3 CGISMVKYILFIFNLLCSICGILLIVFGAL------LFSKVRNMDDFAEALRTQQVPVTM-IILG 60
            ||    ||.||.||::..:.|.|.:..|..      :.|.:..:.|....     .||.: :::|
Human    16 CG----KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGL-----DPVWLFVVVG 71

  Fly    61 TIILLISWFGCCGAIRESYCMSMTYSI---LLFVLMI--GQLALVIYMWVQKDKYLEIMGDVVEK 120
            .::.::.:.||.||:||:..:...:|:   |:|.|.:  |.||.|...|::....|.|..:|  |
Human    72 GVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNV--K 134

  Fly   121 AWNHRTSRSDYMDAIQISMKCCGRSGYTDYAYQGKF--------------PPSCC-----SDTNN 166
            |:.......:.:|..|....|||..|..|:.....|              |.|||     .|..|
Human   135 AYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDVLN 199

  Fly   167 --CRWET-----------VYRRGCKVTFVEFWDRNSDIIKYAGLVIAAIEFVGF----------- 207
              |.::.           ::.:||...| |.|.:::       |::.|..|:|.
Human   200 TQCGYDVRLKLELEQQGFIHTKGCVGQF-EKWLQDN-------LIVVAGVFMGIALLQVPLWPHV 256

  Fly   208 -------------------VFACCLANSI 217
                               :|..|||.::
Human   257 PLPLPGPPSLSPHLSSVLQIFGICLAQNL 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	61/280 (22%)
TSPAN17	NP_001353420.1	Tetraspanin	18..>157	CDD:459767	37/145 (26%)
		TM4SF9_like_LEL	115..235	CDD:239412	27/129 (21%)