Protein Alignment Tsp42Ea and TSPAN15

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_036471.1
• Gene: TSPAN15 / 23555
• HGNCID: 23298
• Length: 294
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 45/239 - (18%)
• Similarity: 111/239 - (46%)
• Gaps: 50/239 - (20%)

  Fly     8 VKYILFIFNLLCSICGILLIVFGALLFSKVRNMDDFAEALRTQQ----VP-VTMIILGTIILLIS 67
            :|:.|.|::.:..:.|.|::..|  ::::|..     :..:|.:    .| :.:|:||.::.::|
Human    20 LKFSLIIYSTVFWLIGALVLSVG--IYAEVER-----QKYKTLESAFLAPAIILILLGVVMFMVS 77

  Fly    68 WFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMGDVVEKAWNHRTSRSDY- 131
            :.|...::|::..:...:..:|.:.:|.:|...:.....:::.::.:.|.:.:...:.....|:
Human    78 FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYDDLDFK 142

  Fly   132 --MDAIQISMKCCGRSGYTDYAYQGKF-------------PPSCC----SDTNN--CRWET---- 171
              ||.:|...||||...|.|:: :.::             |.:||    ::..|  |.::|
Human   143 NIMDFVQKKFKCCGGEDYRDWS-KNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTMCGYKTIDKE 206

  Fly   172 -------VYRRGCKVTFVEFWDRNSDIIKYAGLVIAAI--EFVG 206
                   :|.|||....:.::..|..|:  ||:::..:  :|:|
Human   207 RFSVQDVIYVRGCTNAVIIWFMDNYTIM--AGILLGILLPQFLG 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	45/239 (19%)
TSPAN15	NP_036471.1	Tetraspanin	20..>157	CDD:459767	26/143 (18%)
		penumbra_like_LEL	114..231	CDD:239411	21/117 (18%)