Protein Alignment Tsp42Ea and Tspan33

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_666285.1
• Gene: Tspan33 / 232670
• MGIID: 1919012
• Length: 283
• Species: Mus musculus
• Alignment Length: 262
• Identity: 63/262 - (24%)
• Similarity: 115/262 - (43%)
• Gaps: 45/262 - (17%)

  Fly     7 MVKYILFIFNLLCSICGILLIVFGALLFSKVRNMDDFAEALRTQQVPVTMIILGTIILLISWFGC 71
            :|||:||.||:|..:..::::..|  :::::....:.|.|.......:.:|::|.::.|:::.||
Mouse    21 LVKYLLFFFNMLFWVISMVMVAVG--VYARLMKHAEAALACLAVDPAILLIVVGVLMFLLTFCGC 83

  Fly    72 CGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMGDVVEKAWNHRTSRSDYMDAIQ 136
            .|::||:.|:..|:|:.|.::.:.|||..|..:|..||....:.:::..|..|.....|..:.|.
Mouse    84 IGSLRENICLLQTFSLCLTIVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDDLDLQNLID 148

  Fly   137 ISMK---CCGRSGYTDYAYQGKF--------------PPSCCSDTNN-------C---------- 167
            ...|   |||...|.|::....|              |.|||..|.|       |
Mouse   149 FGQKKFSCCGGISYRDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPNQAVINTMCGQGMQALDYL 213

  Fly   168 -RWETVYRRGCKVTFVEFWDRNSDIIKYAGLVIAAIEFVGFVFACCLANSIR--------NYRRR 223
             ..:.:|..||....|.:...|..::....|.:|..:.||.:.:..|.|.|:        |.:.|
Mouse   214 EASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQVLVNQIKDQIKLQLYNQQHR 278

  Fly   224 AE 225
            |:
Mouse   279 AD 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	58/241 (24%)
Tspan33	NP_666285.1	Tetraspanin	22..262	CDD:459767	58/241 (24%)
		penumbra_like_LEL	116..236	CDD:239411	25/119 (21%)