Protein Alignment Tsp42Ea and tsp-14

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_001367834.1
• Gene: tsp-14 / 180761
• WormBaseID: WBGene00006640
• Length: 451
• Species: Caenorhabditis elegans
• Alignment Length: 294
• Identity: 64/294 - (21%)
• Similarity: 118/294 - (40%)
• Gaps: 93/294 - (31%)

  Fly     8 VKYILFIFNLLCSICGILLIVFGALLFSKVRNMDDFAEALRTQQV--PVTMI-ILGTIILLISWF 69
            :|:::|:.|.:..:.|:.::..|..||.|     ||.|......:  |..:| |.|..|.::|:|
 Worm    54 LKWLVFLLNSIVFLVGVGILALGVYLFIK-----DFREVKLVDIILNPAILISIFGFSICVVSFF 113

  Fly    70 GCCGAIRESYCMSMTYSILLFV--LMIGQLALVIYMWVQKDKYLEIMGDVVEKAW-------NHR 125
            |..||:|::..:...::..:|:  :::..:.||.:.....|     ..:.:...|       |:.
 Worm   114 GFMGALRDNIFLLKCFAACVFLSYILVVAVTLVFFTLFYTD-----TTEGLSANWLLLYAVKNYH 173

  Fly   126 TSR--SDYMDAIQISMKCCGRS----GYTDYAYQGKF--------------PPSCC--------S 162
            |:|  ::.|||:|.:::|||.|    ||.|:....:|              |.|||        :
 Worm   174 TNRNLAEIMDALQENLECCGVSSIAQGYRDWNMSYQFNCTNSNPQPEKCGVPFSCCRKSVISEAA 238

  Fly   163 DTNN----------CRWET------------VYRRGCKVTFVEFWDRNSDIIKYAGLVIAAIEFV 205
            .::|          | |:.            :|.|||.......::.::   .:.|..:|.: .|
 Worm   239 GSSNPLLPAMRSLEC-WQNALTKRPGDLEHDIYTRGCLQPLRTLFESHA---VHVGAFVALL-IV 298

  Fly   206 GFVFACCLANSI----------------RNYRRR 223
            ....:.||.|.:                ||.|||
 Worm   299 PVCISVCLTNILAKQVDHQRYLLEREARRNDRRR 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	58/268 (22%)
tsp-14	NP_001367834.1	Tetraspanin	54..>193	CDD:459767	35/148 (24%)
		tetraspanin_LEL	145..286	CDD:351888	30/146 (21%)