Protein Alignment Tsp42Ea and tsp-12

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_501853.1
• Gene: tsp-12 / 177890
• WormBaseID: WBGene00006638
• Length: 308
• Species: Caenorhabditis elegans
• Alignment Length: 287
• Identity: 66/287 - (22%)
• Similarity: 126/287 - (43%)
• Gaps: 75/287 - (26%)

  Fly     1 MSCGISMVKYILFIFNLLCSICGILLIVFGALLFSKVR-----NMDDFAEALRTQQVPV-TMIIL 59
            :||   .|||.:|.||::..:.|..|::||  :::::.     ||  .::|.:....|. .::|:
 Worm    34 ISC---CVKYSVFSFNVIFFLLGFGLLLFG--VWAQIEKNTFVNM--LSKASKLYLDPTWPLLIV 91

  Fly    60 GTIILLISWFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWV---QKDKYL-EIMGDVVEK 120
            |.:..:|.:.||.|::||:......||.||.:|:|.:.:..::.:.   |.|.|: .::.|||.
 Worm    92 GFLTFIIGFSGCVGSLRENTSFLTFYSTLLGLLLIAEFSAGVFAYACRDQLDNYIRNLLNDVVV- 155

  Fly   121 AWNHRTSRSD-----YMDAIQISMKCCGRSGYTDY---AY------------QGKFPPSCCSDTN 165
                 ..|.|     .:|::|.:..|||.:|..|:   .|            .|..|.|||.:::
 Worm   156 -----GYRDDPDLQLLIDSMQETWMCCGINGADDWDRNTYFSIEAREVASPEAGGVPFSCCINSS 215

  Fly   166 NCRWE------------------------------TVYRRGCKVTFVEFW-DRNSDIIKYAGLVI 199
            ...::                              ::|..|| :..::.| :.|..::..:.::|
 Worm   216 KLEFKNYFCGHGVRLKPESHMAAHLAAQRVMAHTASIYTEGC-LPKLQLWLNNNMLLVAVSMVII 279

  Fly   200 AAIEFVGFVFACCLANSIRNYRRRAEY 226
            |.|:.:|..||..|.:.|...|.:..|
 Worm   280 AIIQVLGICFAQNLKSDILAQRAKWYY 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	61/267 (23%)
tsp-12	NP_501853.1	Tetraspanin	38..293	CDD:459767	60/265 (23%)
		tetraspanin_LEL	133..268	CDD:351888	25/141 (18%)