Protein Alignment Tsp42Ea and Tspan8

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_598210.1
• Gene: Tspan8 / 171048
• RGDID: 621783
• Length: 235
• Species: Rattus norvegicus
• Alignment Length: 233
• Identity: 71/233 - (30%)
• Similarity: 114/233 - (48%)
• Gaps: 30/233 - (12%)

  Fly     4 GIS-MVKYILFIFNLLCSICGILLIVFGALLFSKVRNMDDFAEALRTQQ------VPVTMII-LG 60
            |:| .:||.:|.||.|..:||.|::  |..::.:|..  |..|.:.:..      :.|.::| :|
  Rat     3 GVSGCLKYSMFFFNFLFWVCGTLIL--GLAIWLRVSK--DGKEIITSGDNGTNPFIAVNILIAVG 63

  Fly    61 TIILLISWFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMGD-------VV 118
            :||:::.:.|||||::||.||.:.:.|.|.::::.|:|..|.....|.:...|:.:       ::
  Rat    64 SIIMVLGFLGCCGAVKESRCMLLLFFIGLLLILLLQVAAGILGATFKSESSRILNETLYENAKLL 128

  Fly   119 EKAWNHRTSRSDYMDAIQISMKCCG-RSGYTDYAYQGK-FP---PSC-C--SDTNNCRWETVYRR 175
            .:..|........|.|.|...|||| |.|..|:   || ||   .|| |  ||..:...|.|||.
  Rat   129 SETSNEAKEVQKAMIAFQSEFKCCGLRFGAADW---GKNFPDAKESCQCTGSDCESYNGENVYRT 190

  Fly   176 GCKVTFVEFWDRNSDIIKYAGLVIAAIEFVGFVFACCL 213
            .|.....|..::|..|:......:|.||.:|.||:..|
  Rat   191 TCLSLIKELVEKNIIIVIGIAFGLAVIEILGLVFSMVL 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	69/228 (30%)
Tspan8	NP_598210.1	Tetraspanin	8..230	CDD:459767	69/228 (30%)
		TM4SF3_like_LEL	106..204	CDD:239407	28/100 (28%)