Protein Alignment Tsp42Ea and Cd82

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_031682.1
• Gene: Cd82 / 12521
• MGIID: 104651
• Length: 266
• Species: Mus musculus
• Alignment Length: 274
• Identity: 70/274 - (25%)
• Similarity: 113/274 - (41%)
• Gaps: 56/274 - (20%)

  Fly     1 MSCG-ISMVKYILFIFNLLCSICGILLIVFGALLFSKVRNMDDFAEALRTQ----QVPVTMII-L 59
            |..| :.:.||.||:||||..|.|.:::.||..:.:   :.:.|...|:|.    ||...:.| :
Mouse     1 MGAGCVKVTKYFLFLFNLLFFILGAVILGFGVWILA---DKNSFISVLQTSSSSLQVGAYVFIGV 62

  Fly    60 GTIILLISWFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMGDVV-----E 119
            |.|.:::.:.||.||:.|..|:...|.:.|.:::|.|:.:.:..:...||..:.||:.|     .
Mouse    63 GAITIVMGFLGCIGAVNEVRCLLGLYFVFLLLILIAQVTVGVLFYFNADKLKKEMGNTVMDIIRN 127

  Fly   120 KAWNHRTSRSDYMDAIQISMKCCG------------RSGYTDYAYQGKFPPSC------------ 160
            ...|..:||.:..|.:|..:||||            ..|:|...|    |.||
Mouse   128 YTANATSSREEAWDYVQAQVKCCGWVSHYNWTENEELMGFTKTTY----PCSCEKIKEEDNQLIV 188

  Fly   161 ----C-------SDTNNCRWETVYRRGCKVTFVEFWDRNSDIIKYAGLVIAAIEFVGFVFACCLA 214
                |       |:.|...| .|...||......:...|..|:......:|.||.:|...:.||.
Mouse   189 KKGFCEADNSTVSENNPEDW-PVNTEGCMEKAQAWLQENFGILLGVCAGVAVIELLGLFLSICLC 252

  Fly   215 NSI--RNYRRRAEY 226
            ..|  .:|.:..:|
Mouse   253 RYIHSEDYSKVPKY 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	65/251 (26%)
Cd82	NP_031682.1	Tetraspanin	24..253	CDD:459767	56/236 (24%)
		CD37_CD82_like_LEL	106..228	CDD:239413	28/126 (22%)