Protein Alignment Tsp42Ea and Cd37

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: XP_006540655.1
• Gene: Cd37 / 12493
• MGIID: 88330
• Length: 396
• Species: Mus musculus
• Alignment Length: 280
• Identity: 67/280 - (23%)
• Similarity: 110/280 - (39%)
• Gaps: 72/280 - (25%)

  Fly     2 SCGISMVKYILFIFNLLCSICGILLIVFGA-LLFSKVRNMDDFAEALRTQQVPV-----TMIILG 60
            || :|::||.||:|||...:.|.|:..||. :|..|.    .|...:....||:     .:.:.|
Mouse    28 SC-LSLIKYFLFVFNLFFFVLGGLIFCFGTWILIDKT----SFVSFVGLSFVPLQTWSKVLAVSG 87

  Fly    61 TIILLISWFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLE--IMGDVVEKAWN 123
            .:.:.::..||.||::|..|:...|..:|.:|...|:.|.|.:..|:.: ||  :...|:....:
Mouse    88 VLTMALALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRVR-LERRVQELVLRTIQS 151

  Fly   124 HR-----TSRSDYMDAIQISMKCCGRSGYTDY---------AYQGKFPPSCCSDTNNCRWETV-- 172
            :|     |:..:..|..|..::|||.....|:         ..:..|.|..|.::......||
Mouse   152 YRTNPDETAAEESWDYAQFQLRCCGWQSPRDWNKAQMLKANESEEPFVPCSCYNSTATNDSTVFD 216

  Fly   173 -------------------------------YRRGCKVTFVEFWDRNSDIIKYAG--LVIAAIEF 204
                                           ||.||..: ::.|..| :||...|  |.:..:|.
Mouse   217 KLFFSQLSRLGPRAKLRQTADICALPAKAHIYREGCAQS-LQKWLHN-NIISIVGICLGVGLLEV 279

  Fly   205 VGFVFACCLANSIRNYRRRA 224
            .|  .|.||     ..:|||
Mouse   280 SG--MALCL-----QLQRRA 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	61/263 (23%)
Cd37	XP_006540655.1	Tetraspanin	48..>176	CDD:459767	31/132 (23%)
		CD37_CD82_like_LEL	130..265	CDD:239413	23/137 (17%)