Protein Alignment Tsp42Ea and UPK1A

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: XP_054175633.1
• Gene: UPK1A / 11045
• HGNCID: 12577
• Length: 313
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 42/212 - (19%)
• Similarity: 75/212 - (35%)
• Gaps: 78/212 - (36%)

  Fly    44 AEALRTQQVPVTMIILGTIILLIS----------------------------------W------ 68
            |||.:...|.|.::::|.||:|:|                                  |
Human     8 AEAEKGSPVVVGLLVVGNIIILLSGLSLFAETIWVTADQYRVYPLMGVSGKDDVFAGAWIAIFCG 72

  Fly    69 --------FGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMGDVVEKAWNHR 125
                    ||...|:.....|.:||.:|:.::.|.:.|..|..:..:|..:.....:.::.....
Human    73 FSFFMVASFGVGAALCRRRSMVLTYLVLMLIVYIFECASCITSYTHRDYMVSNPSLITKQMLTFY 137

  Fly   126 TSRSD-------YMDAIQISMKCCGRSGYTDY-----AYQG-------KFPPSCCSDTNN----- 166
            ::.:|       ..|.:.|..:|||.||..|:     |::.       .:||.||..|.|
Human   138 SADTDQGQELTRLWDRVMIEQECCGTSGPMDWVNFTSAFRAATPEVVFPWPPLCCRRTGNFIPLN 202

  Fly   167 ---CR---WETVYRRGC 177
               ||   .:.::.:||
Human   203 EEGCRLGHMDYLFTKGC 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	42/212 (20%)
UPK1A	XP_054175633.1	Tetraspanin	25..>163	CDD:459767	21/137 (15%)
		uroplakin_I_like_LEL	113..231	CDD:239409	22/107 (21%)