Protein Alignment Tsp42Ea and TSPAN2

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_005716.2
• Gene: TSPAN2 / 10100
• HGNCID: 20659
• Length: 221
• Species: Homo sapiens
• Alignment Length: 233
• Identity: 55/233 - (23%)
• Similarity: 100/233 - (42%)
• Gaps: 36/233 - (15%)

  Fly     4 GISMVKYILFIFNLLCSICGILLIVFGAL---------LFSKVRNMDDFAEALRTQQVPVTMIIL 59
            |:..:||:|..||||..:.|..:|.||..         |.|:.::.:.|...|      ..::..
Human     7 GLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGL------YVLVGA 65

  Fly    60 GTIILLISWFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMGDVVEKAWNH 124
            |.:::.:.:||||||:|||.|:..::...|.|:...::...::.::.|...:..:..:.|:|:|
Human    66 GALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAYN- 129

  Fly   125 RTSRSDYMDAIQISMKCCGRSGYTDYAYQGKFPPSCCSDTNN------CRWETVYRRGCKVTFVE 183
                 ||       :|..|:...|...:...|  .||...::      |..|.:..:.|......
Human   130 -----DY-------LKDRGKGNGTLITFHSTF--QCCGKESSEQVQPTCPKELLGHKNCIDEIET 180

  Fly   184 FWDRNSDIIKYAGLVIAAIEFVGFVFACCLANSIRNYR 221
            .......:|...|:.||.:...|.:|:..|..:|||.|
Human   181 IISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSR 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	50/221 (23%)
TSPAN2	NP_005716.2	Tetraspanin	11..212	CDD:459767	50/221 (23%)
		CD81_like_LEL	110..186	CDD:239404	15/90 (17%)