DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp42Ea and TSPAN3

DIOPT Version :9

Sequence 1:NP_525012.2 Gene:Tsp42Ea / 59178 FlyBaseID:FBgn0029508 Length:226 Species:Drosophila melanogaster
Sequence 2:NP_005715.1 Gene:TSPAN3 / 10099 HGNCID:17752 Length:253 Species:Homo sapiens


Alignment Length:229 Identity:65/229 - (28%)
Similarity:108/229 - (47%) Gaps:21/229 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 CGISMVKYILFIFNLL-CSICGILLIVFGALLFSKVRNMDDFAEALRTQQVPVTMIILGTIILLI 66
            |||:..|.:|...||: ....|||..| ||.:|....:.|.|.|.:.|....|.:|.:|.::.:|
Human     4 CGITSSKTVLVFLNLIFWGAAGILCYV-GAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFII 67

  Fly    67 SWFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMGDVVEKAW-----NHRT 126
            ...|||..||||.|...|:.|:|.::.:.::.:|:..:|.:.|....:...::|.:     .:..
Human    68 GLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNPD 132

  Fly   127 SRSDYMDAIQISMKCCGRSGYTDYAYQGKF--------PPSCCSDT-NNCRW-----ETVYRRGC 177
            :.|..:|.:|..:.|||...|:|:.....|        |.|||.:| :||..     ..:|..||
Human   133 AASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHPSDLYAEGC 197

  Fly   178 KVTFVEFWDRNSDIIKYAGLVIAAIEFVGFVFAC 211
            :...|:........:.:|.|..|||:.:|.:.||
Human   198 EALVVKKLQEIMMHVIWAALAFAAIQLLGMLCAC 231

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp42EaNP_525012.2 Tetraspannin 8..217 CDD:278750 62/224 (28%)
tetraspanin_LEL 104..188 CDD:239401 23/102 (23%)
TSPAN3NP_005715.1 Tetraspannin 9..232 CDD:395265 62/224 (28%)
TM4SF8_like_LEL 104..210 CDD:239416 23/105 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3882
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1406905at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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