Protein Alignment Tsp42Ea and TSPAN3

DIOPT Version :10

• Sequence 1: NP_525012.2
• Gene: Tsp42Ea / 59178
• FlyBaseID: FBgn0029508
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_005715.1
• Gene: TSPAN3 / 10099
• HGNCID: 17752
• Length: 253
• Species: Homo sapiens
• Alignment Length: 229
• Identity: 65/229 - (28%)
• Similarity: 108/229 - (47%)
• Gaps: 21/229 - (9%)

  Fly     3 CGISMVKYILFIFNLL-CSICGILLIVFGALLFSKVRNMDDFAEALRTQQVPVTMIILGTIILLI 66
            |||:..|.:|...||: ....|||..| ||.:|....:.|.|.|.:.|....|.:|.:|.::.:|
Human     4 CGITSSKTVLVFLNLIFWGAAGILCYV-GAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFII 67

  Fly    67 SWFGCCGAIRESYCMSMTYSILLFVLMIGQLALVIYMWVQKDKYLEIMGDVVEKAW-----NHRT 126
            ...|||..||||.|...|:.|:|.::.:.::.:|:..:|.:.|....:...::|.:     .:..
Human    68 GLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNPD 132

  Fly   127 SRSDYMDAIQISMKCCGRSGYTDYAYQGKF--------PPSCCSDT-NNCRW-----ETVYRRGC 177
            :.|..:|.:|..:.|||...|:|:.....|        |.|||.:| :||..     ..:|..||
Human   133 AASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHPSDLYAEGC 197

  Fly   178 KVTFVEFWDRNSDIIKYAGLVIAAIEFVGFVFAC 211
            :...|:........:.:|.|..|||:.:|.:.||
Human   198 EALVVKKLQEIMMHVIWAALAFAAIQLLGMLCAC 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ea	NP_525012.2	Tetraspanin	8..215	CDD:459767	62/224 (28%)
TSPAN3	NP_005715.1	Tetraspanin	9..235	CDD:459767	62/224 (28%)
		TM4SF8_like_LEL	104..210	CDD:239416	23/105 (22%)