Protein Alignment Tsp42Eb and CD37

DIOPT Version :10

• Sequence 1: NP_724525.1
• Gene: Tsp42Eb / 59177
• FlyBaseID: FBgn0042086
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: XP_005259492.1
• Gene: CD37 / 951
• HGNCID: 1666
• Length: 365
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 68/277 - (24%)
• Similarity: 109/277 - (39%)
• Gaps: 64/277 - (23%)

  Fly     2 NCLSAMFKYLLYLLNLVFVAGGILLIVVGSIMLSTMGNFTAFDGGVNTQTIPI-----CIIVIGS 61
            :||| :.||.|::.||.|...|.|:...|..:|....:|.:|   |....:|:     .:.:.|.
Human     6 SCLS-LIKYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVSF---VGLAFVPLQIWSKVLAISGI 66

  Fly    62 VTFVVAFFGCCGTIRENACCTTIYAICMLILFGLQLALSIWIFAANDKFLSSMGKAVDKAWD--- 123
            .|..:|..||.|.::|..|...:|...:|:||..|:.|.|.|.....:...|:...|:|...
Human    67 FTMGIALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVVEKTIQKYG 131

  Fly   124 ---ENNAAQGYPMDALQLAFSCCG--------------NTGYQQYETVPSSC------------- 158
               |..||: ...|.:|....|||              ..|.:.:. ||.||
Human   132 TNPEETAAE-ESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHR-VPCSCYNLSATNDSTILD 194

  Fly   159 ---------CGYKDRTK----VC----EAEIYSQRPGCRQEFVDFWASNTDLIRWSSLIIALFEL 206
                     .|:..|::    :|    |:.||  |.||.|....:..:|...|....|.:.|.|:
Human   195 KVILPQLSRLGHLARSRHSADICAVPAESHIY--REGCAQGLQKWLHNNLISIVGICLGVGLLEM 257

  Fly   207 GIFIMSCCL-ASAMRKR 222
            .:.::|..| ..|:|::
Human   258 TVMVLSVQLQRRALRRK 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eb	NP_724525.1	Tetraspanin	8..216	CDD:459767	63/263 (24%)
CD37	XP_005259492.1	Tetraspanin	26..266	CDD:459767	56/246 (23%)
		CD37_CD82_like_LEL	108..243	CDD:239413	28/138 (20%)