Protein Alignment Tsp42Eb and UPK1B

DIOPT Version :10

• Sequence 1: NP_724525.1
• Gene: Tsp42Eb / 59177
• FlyBaseID: FBgn0042086
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_008883.2
• Gene: UPK1B / 7348
• HGNCID: 12578
• Length: 260
• Species: Homo sapiens
• Alignment Length: 199
• Identity: 38/199 - (19%)
• Similarity: 64/199 - (32%)
• Gaps: 59/199 - (29%)

  Fly    57 IVIGSVTFVVAFFGCCGTIRENACCTTIYAICMLILFGLQLALSIWI-----FAANDKFLSSMGK 116
            |.:|...|.::..|..|.::.:......|.|.|.|::..::|..|..     |...:.||..|.:
Human    63 IFVGICLFCLSVLGIVGIMKSSRKILLAYFILMFIVYAFEVASCITAATQQDFFTPNLFLKQMLE 127

  Fly   117 AV--------DKAWDENNAAQGYPMDALQLAFSCCGNTG---YQQYETV------------PSSC 158
            ..        |..|..|...:.:  |.|.|..:|||..|   :|:|.:.            |..|
Human   128 RYQNNSPPNNDDQWKNNGVTKTW--DRLMLQDNCCGVNGPSDWQKYTSAFRTENNDADYPWPRQC 190

  Fly   159 CGYKD-----RTKVCEAEI--YSQRPGCRQEFVD---------------------FWASNTDLIR 195
            |...:     ..:.|:..:  :....|| .|.:.                     ||.....:..
Human   191 CVMNNLKEPLNLEACKLGVPGFYHNQGC-YELISGPMNRHAWGVAWFGFAILCWTFWVLLGTMFY 254

  Fly   196 WSSL 199
            ||.:
Human   255 WSRI 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eb	NP_724525.1	Tetraspanin	8..216	CDD:459767	38/199 (19%)
UPK1B	NP_008883.2	Tetraspanin	14..>161	CDD:459767	22/99 (22%)
		uroplakin_I_like_LEL	118..230	CDD:239409	22/114 (19%)