Protein Alignment Tsp42Eb and TSPAN6

DIOPT Version :10

• Sequence 1: NP_724525.1
• Gene: Tsp42Eb / 59177
• FlyBaseID: FBgn0042086
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_003261.1
• Gene: TSPAN6 / 7105
• HGNCID: 11858
• Length: 245
• Species: Homo sapiens
• Alignment Length: 226
• Identity: 58/226 - (25%)
• Similarity: 108/226 - (47%)
• Gaps: 19/226 - (8%)

  Fly     8 FKYLLYLLNLVFVAGGILLIVVGSIMLSTMGNFTAFDGGVNTQ--TIPICIIVIGSVTFVVAFFG 70
            ||.:|.:...:|...|::|:.||.....::.|:.:.   :|.:  .:|..:|..|:|..::..||
Human    17 FKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSL---LNEKATNVPFVLIATGTVIILLGTFG 78

  Fly    71 CCGTIRENACCTTIYAICMLILFGLQLALSIWIFAANDKFLSSMGKAVDKAWDENNAAQGY---P 132
            |..|.|.:|....:||:.:.::|.::|..:|..|....:..:|.....:||..:.|:...|   .
Human    79 CFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNSTGDYRSHA 143

  Fly   133 MDALQLAFSCCGNTGYQQY--------ETVPSSCCGYKDRTKVCEAEIYSQRPGCRQEFVDFWAS 189
            :|.:|....|||.|.|:.:        :..|.|||..:|.|...:|:..:.. ||..:.:....|
Human   144 VDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLEDCTPQRDADKVNNE-GCFIKVMTIIES 207

  Fly   190 NTDLIRWSSLIIALFEL-GIFIMSCCLASAM 219
            ...::...|..:|.|:| ||| ::.||:.|:
Human   208 EMGVVAGISFGVACFQLIGIF-LAYCLSRAI 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eb	NP_724525.1	Tetraspanin	8..216	CDD:459767	56/221 (25%)
TSPAN6	NP_003261.1	Tetraspanin	17..235	CDD:459767	57/222 (26%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	23/97 (24%)