Protein Alignment Tsp42Eb and CD82

DIOPT Version :10

• Sequence 1: NP_724525.1
• Gene: Tsp42Eb / 59177
• FlyBaseID: FBgn0042086
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: XP_047282856.1
• Gene: CD82 / 3732
• HGNCID: 6210
• Length: 308
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 58/248 - (23%)
• Similarity: 100/248 - (40%)
• Gaps: 46/248 - (18%)

  Fly     9 KYLLYLLNLVFVAGGILLIVVGSIMLSTMGNFTAFDGGVNTQTIPI-----CIIVIGSVTFVVAF 68
            ||.|:|.||:|...|.:::..|..:|:...:|.:.   :.|.:..:     ..|.:|:||.::.|
Human    51 KYFLFLFNLIFFILGAVILGFGVWILADKSSFISV---LQTSSSSLRMGAYVFIGVGAVTMLMGF 112

  Fly    69 FGCCGTIRENACCTTIYAICMLILFGLQLALSIWIFAANDKFLSSMGKAV-DKAWDENNAAQGYP 132
            .||.|.:.|..|...:|...:|::...|:......:....|....||..| :...|.|::.:...
Human   113 LGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTELIRDYNSSREDSL 177

  Fly   133 MDA---LQLAFSCCGNTGYQQYE-----------TVPSSC--CGYKD-----RTKVCEA------ 170
            .||   :|....|||...:..:.           |.|.||  .|.:|     |...|||
Human   178 QDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEEDNSLSVRKGFCEAPGNRTQ 242

  Fly   171 --------EIYSQRPGCRQEFVDFWASNTDLIRWSSLIIALFELGIFIMSCCL 215
                    .:|.:  ||.::...:...|..:|....:.:|:.||...::|.||
Human   243 SGNHPEDWPVYQE--GCMEKVQAWLQENLGIILGVGVGVAIIELLGMVLSICL 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eb	NP_724525.1	Tetraspanin	8..216	CDD:459767	58/248 (23%)
CD82	XP_047282856.1	Tetraspanin	65..295	CDD:459767	51/234 (22%)
		CD37_CD82_like_LEL	147..270	CDD:239413	26/124 (21%)