Protein Alignment Tsp42Eb and TSPAN17

DIOPT Version :10

• Sequence 1: NP_724525.1
• Gene: Tsp42Eb / 59177
• FlyBaseID: FBgn0042086
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_001353420.1
• Gene: TSPAN17 / 26262
• HGNCID: 13594
• Length: 355
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 60/242 - (24%)
• Similarity: 102/242 - (42%)
• Gaps: 47/242 - (19%)

  Fly     9 KYLLYLLNLVFVAGGILLIVVG------SIMLSTMGNFTAFDGGVNTQTIPICI-IVIGSVTFVV 66
            ||.|:..|:||...|.|.:.:|      ..:||.:...|.. ||::    |:.: :|:|.|..|:
Human    18 KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDL-GGLD----PVWLFVVVGGVMSVL 77

  Fly    67 AFFGCCGTIRENACCTTIYAICMLILFGLQLALSIWIFAANDKFLSSMGKAVD---KAWDENNAA 128
            .|.||.|.:|||......:::.:.::|.|:||..|..|...|.....:...::   ||:.::...
Human    78 GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYRDDIDL 142

  Fly   129 QGYPMDALQLAFSCCGNTGYQQYET-----------------VPSSC-------------CGYKD 163
            |.. :|..|..:||||..|...:..                 ||.||             |||..
Human   143 QNL-IDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDVLNTQCGYDV 206

  Fly   164 RTKV-CEAEIYSQRPGCRQEFVDFWASNTDLIRWSSLIIALFELGIF 209
            |.|: .|.:.:....||..:|..:...|..::....:.|||.::.::
Human   207 RLKLELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQVPLW 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eb	NP_724525.1	Tetraspanin	8..216	CDD:459767	60/242 (25%)
TSPAN17	NP_001353420.1	Tetraspanin	18..>157	CDD:459767	40/144 (28%)
		TM4SF9_like_LEL	115..235	CDD:239412	25/120 (21%)