Protein Alignment Tsp42Eb and TSPAN12

DIOPT Version :10

• Sequence 1: NP_724525.1
• Gene: Tsp42Eb / 59177
• FlyBaseID: FBgn0042086
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_036470.1
• Gene: TSPAN12 / 23554
• HGNCID: 21641
• Length: 305
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 54/254 - (21%)
• Similarity: 94/254 - (37%)
• Gaps: 47/254 - (18%)

  Fly     1 MNCLSAMFKYLLYLLNLVFVAGGILLIVVGSIMLSTMGNF------TAFDGGVNTQTIPI---CI 56
            :.||    :.|||.|||:|....|.::.|.:.|...:.|.      |..:..|.....|:   .:
Human     7 VKCL----RCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVM 67

  Fly    57 IVIGSVTFVVAFFGCCGTIRENACCTTIYAICMLILFGLQLALSIWIFAANDKFLSSMGKAVDKA 121
            |.:.....:|...|.|||::.|......|...:|::|.::||..:|.:        .....|...
Human    68 IAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTY--------EQELMVPVQ 124

  Fly   122 WDE------NNAAQGYP--------MDALQLAFSCCGNTGYQQY------ETVPSSCC--GYKDR 164
            |.:      .....|.|        .:..|..|.|||...:..:      :..|.|||  .:...
Human   125 WSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWPPDSCCVREFPGC 189

  Fly   165 TKVCEAEIYSQ--RPGCRQEFVDFWASNTDL--IRWSSLIIALFELGIFIMSCCLASAM 219
            :|....|..|.  :.||.::...|......|  :|:..:.|.:.::...|::..|..|:
Human   190 SKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTITLLWAL 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eb	NP_724525.1	Tetraspanin	8..216	CDD:459767	50/242 (21%)
TSPAN12	NP_036470.1	Tetraspanin	10..246	CDD:459767	52/247 (21%)
		TM4SF12_like_LEL	116..218	CDD:239410	19/101 (19%)