Protein Alignment Tsp42Eb and tsp-14

DIOPT Version :10

• Sequence 1: NP_724525.1
• Gene: Tsp42Eb / 59177
• FlyBaseID: FBgn0042086
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_001367834.1
• Gene: tsp-14 / 180761
• WormBaseID: WBGene00006640
• Length: 451
• Species: Caenorhabditis elegans
• Alignment Length: 275
• Identity: 70/275 - (25%)
• Similarity: 109/275 - (39%)
• Gaps: 67/275 - (24%)

  Fly     4 LSAMFKYLLYLLN-LVFVAG-GILLIVVGSIMLSTMGNFTAFDGGVNTQTIPICIIVIGSVTFVV 66
            :||..|:|::||| :||:.| |||.:.| .:.:.........|..:|.   .|.|.:.|....||
 Worm    50 ISACLKWLVFLLNSIVFLVGVGILALGV-YLFIKDFREVKLVDIILNP---AILISIFGFSICVV 110

  Fly    67 AFFGCCGTIRENACCTTIYAICMLILFGLQLALSIWIFAANDKFLSSMGKAVDKAWDENNAAQGY 131
            :|||..|.:|:|......:|.|:.:.:.|.:|:::..|..   |.:...:.:...|....|.:.|
 Worm   111 SFFGFMGALRDNIFLLKCFAACVFLSYILVVAVTLVFFTL---FYTDTTEGLSANWLLLYAVKNY 172

  Fly   132 P--------MDALQLAFSCCG-----------NTGYQ--------QYET--VPSSCC-------- 159
            .        |||||....|||           |..||        |.|.  ||.|||
 Worm   173 HTNRNLAEIMDALQENLECCGVSSIAQGYRDWNMSYQFNCTNSNPQPEKCGVPFSCCRKSVISEA 237

  Fly   160 -GYKD------RTKVCEAEIYSQRP----------GCRQEFVDFWASNTDLIRWSSLIIALFELG 207
             |..:      |:..|.....::||          ||.|.....:.|:...:   ...:||..:.
 Worm   238 AGSSNPLLPAMRSLECWQNALTKRPGDLEHDIYTRGCLQPLRTLFESHAVHV---GAFVALLIVP 299

  Fly   208 IFIMSCCLASAMRKR 222
            :.| |.||.:.:.|:
 Worm   300 VCI-SVCLTNILAKQ 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eb	NP_724525.1	Tetraspanin	8..216	CDD:459767	66/263 (25%)
tsp-14	NP_001367834.1	Tetraspanin	54..>193	CDD:459767	40/145 (28%)
		tetraspanin_LEL	145..286	CDD:351888	32/143 (22%)