Protein Alignment Tsp42Eb and Tspan8

DIOPT Version :10

• Sequence 1: NP_724525.1
• Gene: Tsp42Eb / 59177
• FlyBaseID: FBgn0042086
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_598210.1
• Gene: Tspan8 / 171048
• RGDID: 621783
• Length: 235
• Species: Rattus norvegicus
• Alignment Length: 249
• Identity: 63/249 - (25%)
• Similarity: 102/249 - (40%)
• Gaps: 53/249 - (21%)

  Fly     4 LSAMFKYLLYLLNLVF-VAGGILLIVVGSIMLSTMGN--FTAFDGGVNTQTIPICIIVIGSVTFV 65
            :|...||.::..|.:| |.|.::|.:...:.:|..|.  .|:.|.|.|.......:|.:||:..|
  Rat     4 VSGCLKYSMFFFNFLFWVCGTLILGLAIWLRVSKDGKEIITSGDNGTNPFIAVNILIAVGSIIMV 68

  Fly    66 VAFFGCCGTIRENACCTTIYAICMLILFGLQLALSIW--------------IFAANDKFL---SS 113
            :.|.||||.::|:.|...::.|.:|::..||:|..|.              ....|.|.|   |:
  Rat    69 LGFLGCCGAVKESRCMLLLFFIGLLLILLLQVAAGILGATFKSESSRILNETLYENAKLLSETSN 133

  Fly   114 MGKAVDKAWDENNAAQGYPMDALQLAFSCCG------NTGYQQYETVPSSC-CGYKDRTKVCEA- 170
            ..|.|.||           |.|.|..|.|||      :.| :.:.....|| |...|    ||:
  Rat   134 EAKEVQKA-----------MIAFQSEFKCCGLRFGAADWG-KNFPDAKESCQCTGSD----CESY 182

  Fly   171 ---EIYSQRPGCRQEFVDFWASNTDLIRWSSLIIALFE-LGI---FIMSCCLAS 217
               .:|  |..|.....:....|..::...:..:|:.| ||:   .::.|.:.|
  Rat   183 NGENVY--RTTCLSLIKELVEKNIIIVIGIAFGLAVIEILGLVFSMVLYCQIGS 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eb	NP_724525.1	Tetraspanin	8..216	CDD:459767	61/242 (25%)
Tspan8	NP_598210.1	Tetraspanin	8..230	CDD:459767	60/239 (25%)
		TM4SF3_like_LEL	106..204	CDD:239407	25/115 (22%)