Protein Alignment Tsp42Eb and TSPAN19

DIOPT Version :10

• Sequence 1: NP_724525.1
• Gene: Tsp42Eb / 59177
• FlyBaseID: FBgn0042086
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_001094387.1
• Gene: TSPAN19 / 144448
• HGNCID: 31886
• Length: 248
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 61/236 - (25%)
• Similarity: 97/236 - (41%)
• Gaps: 33/236 - (13%)

  Fly     2 NCLSAMFKYLLYLLNLVFVAGGILLIVVGSIMLSTMGNF-TAFDGGVNTQTIPICIIVI--GSVT 63
            |..:.:.||.|.|:|..|:..|:|.:..|:.:|....|| ||||.. |...:||..|:|  ||.|
Human     4 NNKTIIIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDEN-NHFIVPISQILIGMGSST 67

  Fly    64 FVVAFFGCCGTIRENACCTTIYAICMLILFGLQLALSIWIFAANDK----------FLSSMGKAV 118
            .:....|..|...|......:||:.:...|.:|:.||.:|....::          |:.|...:.
Human    68 VLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISEYGSK 132

  Fly   119 DKAWDENNAAQGYPMDALQLAFSCCGNTGYQQY---------ETVPSSCCGYKDRTKVCEAEI-- 172
            ||..|   ..:...::|||....|||...|..:         ..||.||.....|...|:..:
Human   133 DKPED---ITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTKSTLRKWFCDEPLNA 194

  Fly   173 -YSQRPGCRQEFVDFWASNTDLIRWSSLIIALFELGIFIMS 212
             |.:  ||..: :..| .|.:::....:...|....:|.:|
Human   195 TYLE--GCENK-ISAW-YNVNVLTLIGINFGLLTSEVFQVS 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eb	NP_724525.1	Tetraspanin	8..216	CDD:459767	60/230 (26%)
TSPAN19	NP_001094387.1	Tetraspanin	10..>155	CDD:459767	43/148 (29%)
		CD37_CD82_like_LEL	107..212	CDD:239413	24/111 (22%)