Protein Alignment Tsp42Eb and TSPAN1

DIOPT Version :10

• Sequence 1: NP_724525.1
• Gene: Tsp42Eb / 59177
• FlyBaseID: FBgn0042086
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: XP_011538762.1
• Gene: TSPAN1 / 10103
• HGNCID: 20657
• Length: 258
• Species: Homo sapiens
• Alignment Length: 188
• Identity: 41/188 - (21%)
• Similarity: 69/188 - (36%)
• Gaps: 42/188 - (22%)

  Fly     1 MNCLS------AMFKYLLYLLNLVFVAGGILLIVVGSIMLSTMGNFTAFDGGVNTQTIPICIIVI 59
            |.|.|      .:|..|::|.....:|.||.:.:.|:..|...|..::  ..:....:...:|..
Human     1 MQCFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSS--SAMQFVNVGYFLIAA 63

  Fly    60 GSVTFVVAFFGCCGTIRENACCTTIYAICMLILFGLQLALSIWIFAAN---DKFLSSM------- 114
            |.|.|.:.|.||.|...|:.|....:...:|::|..::|.::......   :.||:.:
Human    64 GVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAIKK 128

  Fly   115 --GKAVD--KAWDENNAAQGYPMDALQLAFSCCGNTGYQQYE---------TVPSSCC 159
              |...|  :.|  |...:|         ..|||.|.|..:|         ..|..||
Human   129 DYGSQEDFTQVW--NTTMKG---------LKCCGFTNYTDFEDSPYFKENSAFPPFCC 175

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eb	NP_724525.1	Tetraspanin	8..216	CDD:459767	38/175 (22%)
TSPAN1	XP_011538762.1	Tetraspanin	7..>151	CDD:459767	30/156 (19%)
		uroplakin_I_like_LEL	110..212	CDD:239409	16/77 (21%)