Protein Alignment Tsp42Eb and TSPAN3

DIOPT Version :10

• Sequence 1: NP_724525.1
• Gene: Tsp42Eb / 59177
• FlyBaseID: FBgn0042086
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_005715.1
• Gene: TSPAN3 / 10099
• HGNCID: 17752
• Length: 253
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 56/235 - (23%)
• Similarity: 104/235 - (44%)
• Gaps: 26/235 - (11%)

  Fly     9 KYLLYLLNLVFVAGGILLIVVGSIMLSTMGNFTAFDGGVNTQTIPICIIVIGSVTFVVAFFGCCG 73
            |.:|..|||:|.....:|..||:.:..|..::..|...|.|....:.||.:|::.|::...|||.
Human    10 KTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGLIGCCA 74

  Fly    74 TIRENACCTTIYAICMLILFGLQLALSIWIFAANDKFLSSMGKAVDKAWDENNA----AQGYPMD 134
            ||||:.|....:.|.:|::|..::.:.:..:....|..:.:.:::.|.:...|.    |....:|
Human    75 TIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNPDAASRAID 139

  Fly   135 ALQLAFSCCGNTGYQQYE-----------TVPSSCCGYKDRTKVCE------AEIYSQRPGCRQE 182
            .:|....|||...|..:|           :||.|||  ::....|.      :::|::  ||...
Human   140 YVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCC--RETASNCNGSLAHPSDLYAE--GCEAL 200

  Fly   183 FVDFWASNTDLIRWSSLIIALFELGIFIMSCCLASAMRKR 222
            .|.........:.|::|..|..:| :.::..|:....|.|
Human   201 VVKKLQEIMMHVIWAALAFAAIQL-LGMLCACIVLCRRSR 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eb	NP_724525.1	Tetraspanin	8..216	CDD:459767	54/227 (24%)
TSPAN3	NP_005715.1	Tetraspanin	9..235	CDD:459767	54/229 (24%)
		TM4SF8_like_LEL	104..210	CDD:239416	21/109 (19%)