Protein Alignment Tsp42Eb and TSPAN5

DIOPT Version :10

• Sequence 1: NP_724525.1
• Gene: Tsp42Eb / 59177
• FlyBaseID: FBgn0042086
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_005714.2
• Gene: TSPAN5 / 10098
• HGNCID: 17753
• Length: 268
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 64/266 - (24%)
• Similarity: 102/266 - (38%)
• Gaps: 75/266 - (28%)

  Fly     4 LSAMFKYLLYLLNLVFVAGGILLIVVG------SIMLSTMGNFTAFDGGVNTQTIPICI-IVIGS 61
            :|...||.::..|::|...||..:.:|      ..:||.:.:.|.. ||.:    |:.: :|:|.
Human    11 VSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDL-GGFD----PVWLFLVVGG 70

  Fly    62 VTFVVAFFGCCGTIRENACCTTIYAICMLILFGLQLALSIWIFAANDKFLSSMGKAVDKAW--DE 124
            |.|::.|.||.|.:|||......:::.:.|:|.|:|...:..|             |.|.|  |:
Human    71 VMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAF-------------VFKDWIKDQ 122

  Fly   125 -----NNAAQGYP--------MDALQLAFSCCGNTGYQQYET-----------------VPSSC- 158
                 ||..:.|.        :|..|..:.|||..|...:..                 ||.||
Human   123 LYFFINNNIRAYRDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRERCGVPFSCC 187

  Fly   159 ------------CGYKDRTK-VCEAEIYSQRPGCRQEFVDFWASNTDLIRWSSLIIALFELGIFI 210
                        |||..|.| ..:.:|.....||..:|..:...|..::....:.|||.:    |
Human   188 TKDPAEDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGIALLQ----I 248

  Fly   211 MSCCLA 216
            ...|||
Human   249 FGICLA 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eb	NP_724525.1	Tetraspanin	8..216	CDD:459767	61/260 (23%)
TSPAN5	NP_005714.2	Tetraspanin	15..258	CDD:459767	63/262 (24%)
		TM4SF9_like_LEL	113..233	CDD:239412	27/132 (20%)