DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18815 and lypla2

DIOPT Version :9

Sequence 1:	NP_001261719.1	Gene:	CG18815 / 59176	FlyBaseID:	FBgn0042138	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_957043.1	Gene:	lypla2 / 393722	ZFINID:	ZDB-GENE-040426-1715	Length:	232	Species:	Danio rerio

Alignment Length:	223	Identity:	124/223 - (55%)
Similarity:	156/223 - (69%)	Gaps:	11/223 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAAPVIVEA-----TVKQTATLIFMHGLGDTGHGWSSALAAIRPPFMKVICPTAPTQPVSLNAGF 60
            |:.|::.||     |.|:||.:||:||||||||||:.|:.:||.|::|.|||.||..||:||...
Zfish     6 MSVPLLAEAVTVPGTEKETAVVIFLHGLGDTGHGWADAMTSIRLPYIKYICPHAPRIPVTLNLKM 70

  Fly    61 RMPSWFDLKTLDIGGPEDEPGIQSARDSVHGMIQKEISAGIPANRIVLGGFSQGGALALYSALTY 125
            .|||||||..|....||||.||:.|.:::..:|..|:..|||:||||||||||||||:||:|||.
Zfish    71 TMPSWFDLMGLSPESPEDEAGIKRAAENIKAIIDHEVKNGIPSNRIVLGGFSQGGALSLYTALTS 135

  Fly   126 DQPLAGVVALSCWLPLHKQFP---GAKVNSDDVPIFQAHGDYDPVVPYKFGQLSASLLKSFM--K 185
            .|.|||||.|||||||||.||   ||..|. |.||.|.||:.||::|.:||.::|..||:.:  :
Zfish   136 QQQLAGVVGLSCWLPLHKTFPQAAGASANK-DTPILQCHGEMDPMIPVQFGAMTAEKLKTIVSPE 199

  Fly   186 NVTFKTYSGLSHSSSDDEMDDVKDIISK 213
            |:||:||.||.|||...||..|||.|.|
Zfish   200 NITFRTYPGLMHSSCPQEMSAVKDFIEK 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18815	NP_001261719.1	Abhydrolase_2	4..214	CDD:280406	123/220 (56%)
lypla2	NP_957043.1	Abhydrolase_2	14..227	CDD:280406	120/213 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	245	1.000	Domainoid score	I2145
eggNOG	1	0.900	-	-		E1_COG0400
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H100964
Inparanoid	1	1.050	247	1.000	Inparanoid score	I3249
OMA	1	1.010	-	-		QHG53978
OrthoDB	1	1.010	-	-		D1373549at2759
OrthoFinder	1	1.000	-	-		FOG0000652
OrthoInspector	1	1.000	-	-		otm24372
orthoMCL	1	0.900	-	-		OOG6_100696
Panther	1	1.100	-	-	LDO	PTHR10655
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R75
SonicParanoid	1	1.000	-	-		X443
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.910