DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18815 and Lypla1

DIOPT Version :9

Sequence 1:	NP_001261719.1	Gene:	CG18815 / 59176	FlyBaseID:	FBgn0042138	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_032892.1	Gene:	Lypla1 / 18777	MGIID:	1344588	Length:	230	Species:	Mus musculus

Alignment Length:	219	Identity:	118/219 - (53%)
Similarity:	146/219 - (66%)	Gaps:	6/219 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAAPV--IVEATVKQTATLIFMHGLGDTGHGWSSALAAIRPPFMKVICPTAPTQPVSLNAGFRMP 63
            |:||:  :|.|..|.||.:||:||||||||||:.|.|.|:.|.:|.|||.||..||:||....||
Mouse     6 MSAPMPAVVPAARKATAAVIFLHGLGDTGHGWAEAFAGIKSPHIKYICPHAPVMPVTLNMNMAMP 70

  Fly    64 SWFDLKTLDIGGPEDEPGIQSARDSVHGMIQKEISAGIPANRIVLGGFSQGGALALYSALTYDQP 128
            ||||:..|.....|||.||:.|.::|..:|.:|:..|||:|||:||||||||||:||:|||..|.
Mouse    71 SWFDIVGLSPDSQEDESGIKQAAETVKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQK 135

  Fly   129 LAGVVALSCWLPLHKQFPGAKVNS--DDVPIFQAHGDYDPVVPYKFGQLSASLLKSFMK--NVTF 189
            ||||.||||||||...|....:||  .|:.:.|.|||.||:||..||.|:...||:.:.  ||||
Mouse   136 LAGVTALSCWLPLRASFSQGPINSANRDISVLQCHGDCDPLVPLMFGSLTVERLKALINPANVTF 200

  Fly   190 KTYSGLSHSSSDDEMDDVKDIISK 213
            |.|.|:.|||...||.|||..|.|
Mouse   201 KIYEGMMHSSCQQEMMDVKHFIDK 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18815	NP_001261719.1	Abhydrolase_2	4..214	CDD:280406	116/216 (54%)
Lypla1	NP_032892.1	Abhydrolase_2	11..226	CDD:280406	115/214 (54%)
Lypla1	NP_032892.1	MhpC	24..>155	CDD:223669	77/130 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846980
Domainoid	1	1.000	235	1.000	Domainoid score	I2351
eggNOG	1	0.900	-	-		E1_COG0400
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	235	1.000	Inparanoid score	I3392
Isobase	1	0.950	-	0.993157	Normalized mean entropy	S960
OMA	1	1.010	-	-		QHG53978
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000652
OrthoInspector	1	1.000	-	-		otm44176
orthoMCL	1	0.900	-	-		OOG6_100696
Panther	1	1.100	-	-	LDO	PTHR10655
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R75
SonicParanoid	1	1.000	-	-		X443
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.780