Protein Alignment CG18815 and LYPLA2

DIOPT Version :9

• Sequence 1: NP_001261719.1
• Gene: CG18815 / 59176
• FlyBaseID: FBgn0042138
• Length: 232
• Species: Drosophila melanogaster
• Sequence 2: XP_024308564.1
• Gene: LYPLA2 / 11313
• HGNCID: 6738
• Length: 287
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 118/265 - (44%)
• Similarity: 152/265 - (57%)
• Gaps: 52/265 - (19%)

  Fly     1 MAAPVIVEATV-----KQTATLIFMHGLGDTGHGWSSALAAIRPPFMKVICPTAPTQPVSLNAGF 60
            |:.|::.:|..     ::||.:||:||||||||.|:.||:.||.|.:|.|||.||..||:||...
Human    18 MSVPLLTDAATVSGAERETAAVIFLHGLGDTGHSWADALSTIRLPHVKYICPHAPRIPVTLNMKM 82

  Fly    61 RMPSWFDLKTLDIGGPEDEPGIQSARDS------------------------------------- 88
            .|||||||..|....||||.||:.|.::
Human    83 VMPSWFDLMGLSPDAPEDEAGIKKAAENSKTPAPPPHPPSPAPQESAGRFLSLAPLLGPLAASLY 147

  Fly    89 -------VHGMIQKEISAGIPANRIVLGGFSQGGALALYSALTYDQPLAGVVALSCWLPLHKQFP 146
                   |..:|:.|:..||||||||||||||||||:||:|||...||||:||||||||||:.||
Human   148 PLMPPPPVKALIEHEMKNGIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCWLPLHRAFP 212

  Fly   147 -GAKVNSDDVPIFQAHGDYDPVVPYKFGQLSASLLKSFM--KNVTFKTYSGLSHSSSDDEMDDVK 208
             .|..::.|:.|.|.||:.||:||.:||.|:|..|:|.:  ..|.||||.|:.|||...||..||
Human   213 QAANGSAKDLAILQCHGELDPMVPVRFGALTAEKLRSVVTPARVQFKTYPGVMHSSCPQEMAAVK 277

  Fly   209 DIISK 213
            :.:.|
Human   278 EFLEK 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18815	NP_001261719.1	Abhydrolase_2	4..214	CDD:280406	117/262 (45%)
LYPLA2	XP_024308564.1	Abhydrolase_2	26..284	CDD:280406	116/257 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	235	1.000	Domainoid score	I2372
eggNOG	1	0.900	-	-		E1_COG0400
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H100964
Inparanoid	1	1.050	235	1.000	Inparanoid score	I3404
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53978
OrthoDB	1	1.010	-	-		D1373549at2759
OrthoFinder	1	1.000	-	-		FOG0000652
OrthoInspector	1	1.000	-	-		otm42120
orthoMCL	1	0.900	-	-		OOG6_100696
Panther	1	1.100	-	-	LDO	PTHR10655
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R75
SonicParanoid	1	1.000	-	-		X443
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.910