DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18814 and NQR

DIOPT Version :9

Sequence 1:	NP_652673.2	Gene:	CG18814 / 59175	FlyBaseID:	FBgn0042137	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_001185182.1	Gene:	NQR / 841391	AraportID:	AT1G49670	Length:	652	Species:	Arabidopsis thaliana

Alignment Length:	217	Identity:	61/217 - (28%)
Similarity:	101/217 - (46%)	Gaps:	40/217 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 GKNVVYLGGFGGIGKKCVQELLKKQIKGLAIFDLIVDDDLLAEWKKQHPDTEI------FYQ--- 60
            |.:.:..||..|||:.....|.:|     .:|..:.|   .:|.|.|...:.:      |:|
plant     6 GLSALVTGGASGIGRALCLALAEK-----GVFVTVAD---FSEEKGQETTSLVREANAKFHQGLS 62

  Fly    61 -------KMDITQKSDIDAAYKATAEKLGHFDVVVNGSGLLDDRRIEL-----------TIQINL 107
                   |.|:|.:.|:.||:.......|..|:.:|.:|:....|.:.           ||.::|
plant    63 FPSAIFVKCDVTNRGDLLAAFDKHLATFGTLDICINNAGISTPLRFDKDDTDGSKSWKHTINVDL 127

  Fly   108 VGVINSTLTALEYMDKSKGGRGGLIVNISSVAGLQPTPLMAIYSTSKTGVTTFTRAMASPIHYAH 172
            :.|:..|..|::.| |:| .:.|:|:|:.|.|||.|.|:..||:.||.||..|||::|   :|..
plant   128 IAVVEGTQLAIKAM-KAK-QKPGVIINMGSAAGLYPMPVDPIYAASKAGVVLFTRSLA---YYRR 187

  Fly   173 SGVGFITICPGYTNTGILKDID 194
            .|:....:||.:..|.:.:.||
plant   188 QGIRINVLCPEFIKTDLAEAID 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18814	NP_652673.2	NADB_Rossmann	6..248	CDD:304358	60/216 (28%)
CG18814	NP_652673.2	adh_short	6..196	CDD:278532	60/216 (28%)
NQR	NP_001185182.1	ADH_SDR_c_like	9..254	CDD:187584	60/214 (28%)
		adh_short	9..210	CDD:278532	60/214 (28%)
		CurA	285..639	CDD:225041
		Mgc45594_like	286..640	CDD:176212
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	96	1.000	Domainoid score	I2453
eggNOG	1	0.900	-	-		E2759_KOG4169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2961
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810