Protein Alignment CG18814 and Hpgd

DIOPT Version :9

• Sequence 1: NP_652673.2
• Gene: CG18814 / 59175
• FlyBaseID: FBgn0042137
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_077366.2
• Gene: Hpgd / 79242
• RGDID: 620087
• Length: 266
• Species: Rattus norvegicus
• Alignment Length: 269
• Identity: 83/269 - (30%)
• Similarity: 128/269 - (47%)
• Gaps: 34/269 - (12%)

  Fly     1 MDLEGKNVVYLGGFGGIGKKCVQELLKKQIKGLAIFDLIVDDDLLAEWKKQ-------------H 52
            |.:.||..:..|...||||...:.||   :.|..:        .|.:|..:             .
  Rat     1 MHVNGKVALVTGAAQGIGKAFTEALL---LHGAKV--------ALVDWNLETGVKCKAALDEQFE 54

  Fly    53 PDTEIFYQKMDITQKSDIDAAYKATAEKLGHFDVVVNGSGLLDDRRIELTIQINLVGVINSTLTA 117
            |...:|.| .|:..:..:...::...:..|..|::||.:|:.:::..|.|:|||||.||:.|...
  Rat    55 PQKTLFIQ-CDVADQKQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVISGTYLG 118

  Fly   118 LEYMDKSKGGRGGLIVNISSVAGLQPTPLMAIYSTSKTGVTTFTRAMASPIHYAHSGVGFITICP 182
            |:||.|..||.||:|:||||:|||.|.....:|..||.|:..|||:.|...:...|||....|||
  Rat   119 LDYMSKQNGGEGGIIINISSIAGLMPVAQQPVYCASKHGIIGFTRSAAMAANLMKSGVRLNVICP 183

  Fly   183 GYTNTGILKDIDKKTTFPFY-----ETRMRTVFSKVKGQTAEVCARNIVNAIE-TAKNGAVLMLE 241
            |:..|.||:.|:|:.....|     :.:....|..:...:|  .|..::|.|| .|.|||::.:.
  Rat   184 GFVKTPILESIEKEENMGQYIEYTDQIKAMMKFYGILDPSA--IANGLINLIEDDALNGAIMKIT 246

  Fly   242 LGE-IHELD 249
            ..: ||..|
  Rat   247 ASKGIHFQD 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18814	NP_652673.2	NADB_Rossmann	6..248	CDD:304358	80/261 (31%)
		adh_short	6..196	CDD:278532	66/202 (33%)
Hpgd	NP_077366.2	ADH_SDR_c_like	6..254	CDD:187584	80/261 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344849
Domainoid	1	1.000	142	1.000	Domainoid score	I4569
eggNOG	1	0.900	-	-		E2759_KOG4169
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	150	1.000	Inparanoid score	I4290
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1053465at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44427
orthoMCL	1	0.900	-	-		OOG6_100916
Panther	1	1.100	-	-	LDO	PTHR44229
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.760