Protein Alignment CG18814 and hsd17b10

DIOPT Version :10

• Sequence 1: NP_652673.2
• Gene: CG18814 / 59175
• FlyBaseID: FBgn0042137
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_001006098.1
• Gene: hsd17b10 / 450078
• ZFINID: ZDB-GENE-041010-201
• Length: 260
• Species: Danio rerio
• Alignment Length: 280
• Identity: 76/280 - (27%)
• Similarity: 113/280 - (40%)
• Gaps: 70/280 - (25%)

  Fly     6 KNVVYL--GGFGGIGKKCVQELLKKQIKGLAIFDLIVDD---------DLLAEWKKQHPDTEIFY 59
            |.:|.|  ||..|:|:..|:.|:|.....: |.||...|         |..|            :
Zfish     8 KGMVGLVTGGASGLGRATVERLIKHGASAV-ILDLPSSDGHKVAAALGDRCA------------F 59

  Fly    60 QKMDITQKSDIDAAYKATAEKLGHFDVVVNGSGL----------------LDDRRIELTIQINLV 108
            ...|:|.:||:.:|.....||.|..|:.||.:|:                |:|  ....|.:|:.
Zfish    60 APTDVTSESDVRSALDLAKEKYGKVDLAVNCAGIAVAVKTYNFKKDLPHSLED--FTRVITVNIA 122

  Fly   109 GVINSTLTALEYMDKSK---GGRGGLIVNISSVAGLQPTPLMAIYSTSKTGVTTFTRAMASPIHY 170
            |..|....|:..|.|::   .|..|.|||.:|||........|.||.||.|:...|..:|..:
Zfish   123 GTFNVIRLAVGEMGKNEPDADGHRGCIVNTASVAAYDGQVGQAAYSASKGGIVGMTLPIARDL-- 185

  Fly   171 AHSGVGFITICPGYTNTGILKDIDKKT------TFPFYETRMRTVFSKVKGQTAEVCARNIVNAI 229
            |..|:..:||.||...|.:|..:.:|.      ..|| .:|:        |..||..  ::|.:|
Zfish   186 APMGIRVVTIAPGLFATPLLAGLPEKVQSFLARQVPF-PSRL--------GDPAEFA--HLVTSI 239

  Fly   230 ETAKNGAVLMLELGEIHELD 249
              |:|..:    .||:..||
Zfish   240 --AENPMI----NGEVIRLD 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18814	NP_652673.2	Rossmann-fold NAD(P)(+)-binding proteins	6..248	CDD:473865	74/277 (27%)
hsd17b10	NP_001006098.1	HSD10-like_SDR_c	8..260	CDD:187629	76/280 (27%)