Protein Alignment CG18814 and Hsd17b10

DIOPT Version :10

• Sequence 1: NP_652673.2
• Gene: CG18814 / 59175
• FlyBaseID: FBgn0042137
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_058043.3
• Gene: Hsd17b10 / 15108
• MGIID: 1333871
• Length: 261
• Species: Mus musculus
• Alignment Length: 265
• Identity: 70/265 - (26%)
• Similarity: 113/265 - (42%)
• Gaps: 44/265 - (16%)

  Fly     3 LEGKNVVYLGGFGGIGKKCVQELLKKQIKGLAIFDLIVDDDLLAEWKKQHPDTEIFYQKMDITQK 67
            ::|...|..||..|:|....:.|:.:  ...|:...:.|.:..|:.||.  .....:...::|.:
Mouse     8 VKGLVAVVTGGASGLGLATAKRLVGQ--GATAVLLDVPDSEGEAQAKKL--GESCIFAPANVTSE 68

  Fly    68 SDIDAAYKATAEKLGHFDVVVNGSGL----------------LDDRRIELTIQINLVGVINSTLT 116
            .:|.||.....||.|..||.||.:|:                |:|  .:..|.:||:|..|....
Mouse    69 KEIQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHQKKNKIHTLED--FQRVINVNLIGTFNVIRL 131

  Fly   117 ALEYM---DKSKGGRGGLIVNISSVAGLQPTPLMAIYSTSKTGVTTFTRAMASPIHYAHSGVGFI 178
            ....|   :..:||:.|:|:|.:|||..:.....|.||.||.|:...|..:|..:  |.:|:..:
Mouse   132 VAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL--APTGIRVV 194

  Fly   179 TICPGYTNTGILKDIDKK------TTFPFYETRMRTVFSKVKGQTAEVCARNIVNAIETA-KNGA 236
            ||.||...|.:|..:.:|      :..|| .:|:        |..||. |..:...||.. .||.
Mouse   195 TIAPGLFATPLLTTLPEKVRNFLASQVPF-PSRL--------GDPAEY-AHLVQTIIENPFLNGE 249

  Fly   237 VLMLE 241
            |:.|:
Mouse   250 VIRLD 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18814	NP_652673.2	Rossmann-fold NAD(P)(+)-binding proteins	6..248	CDD:473865	69/262 (26%)
Hsd17b10	NP_058043.3	HSD10-like_SDR_c	9..261	CDD:187629	70/264 (27%)