Protein Alignment CG18814 and DHRS2

DIOPT Version :10

• Sequence 1: NP_652673.2
• Gene: CG18814 / 59175
• FlyBaseID: FBgn0042137
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_878912.1
• Gene: DHRS2 / 10202
• HGNCID: 18349
• Length: 300
• Species: Homo sapiens
• Alignment Length: 127
• Identity: 30/127 - (23%)
• Similarity: 56/127 - (44%)
• Gaps: 23/127 - (18%)

  Fly   101 LTIQINLVGVINSTLTALEYMDKSKGGRGGLIVNISSVAGLQPTPLMAIYSTSKTGVTTFTRAMA 165
            |::.:....::.|.|  |.||:    .|.|.::.:||:|...|...:.:|:.|||.:...||.:|
Human   142 LSVNVKSPALLLSQL--LPYME----NRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLA 200

  Fly   166 SPIHYAHSGVGFITICPGYTNTGILKDIDKKTTFPFYETRMRTVFSKVKGQTAEVCARNIVN 227
              :..|...:....:.||...|...|.:           |:..:...:.|:|    :|||::
Human   201 --LELAPKDIRVNCVVPGIIKTDFSKVV-----------RIGFMGMSLSGRT----SRNIIS 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18814	NP_652673.2	Rossmann-fold NAD(P)(+)-binding proteins	6..248	CDD:473865	30/127 (24%)
DHRS2	NP_878912.1	Rossmann-fold NAD(P)(+)-binding proteins	27..>226	CDD:473865	24/91 (26%)