DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gdap2 and AT1G69340

DIOPT Version :9

Sequence 1:	NP_724597.1	Gene:	Gdap2 / 59173	FlyBaseID:	FBgn0042135	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001323191.1	Gene:	AT1G69340 / 843266	AraportID:	AT1G69340	Length:	562	Species:	Arabidopsis thaliana

Alignment Length:	551	Identity:	174/551 - (31%)
Similarity:	279/551 - (50%)	Gaps:	60/551 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SSSSSCPVKLDNLATWGGSQKTDTRLPITDYSNLGGPRHNR---------------------SPF 59
            :.|....|.||.:..|   ...:.|..:.|  ..|.|.|:.                     |.|
plant    18 TESGDYVVTLDQIPRW---SDVEQRSSLED--ETGDPEHSNPRYANPLASSSEAGSSGNGMVSKF 77

  Fly    60 PLCKDVNNRFVIWDGDMTTLEVDAITNTSDETLTESNSISERIFAVAGNQLREELSTTVKECRTG 124
            |:..::|:|..:|.|:...|||||:.|:::|.|.|::| |..:...||..|.|:.: |:..||||
plant    78 PVDHEINSRIYLWRGEPWNLEVDAVVNSTNENLDEAHS-SPGLHVAAGPGLAEQCA-TLGGCRTG 140

  Fly   125 DVRITRGYNLPAKYVLHTVAPAYREKFKTAAENTLHCCYRNVLCKAKELNLHTIALCNISAHQKS 189
            ..::|..|:|||:.|:|||.|.|..|:.|||||.|..|||:.|....:..|.:|||..|....|:
plant   141 MAKVTNAYDLPARRVIHTVGPKYAVKYHTAAENALSHCYRSCLELLIDSGLQSIALGCIYTEAKN 205

  Fly   190 FPADVAAHIALRTIRRYLD--KCTLQVVILC-VGSSERGTYEVLAPLYFPRDQLEERSALWQLPK 251
            :|.:.|||:|:||:||:|:  |..:..|:.| ..||:...|:.|.|||||||:.||..|:.:||.
plant   206 YPREPAAHVAIRTVRRFLEKQKDKISAVVFCTTTSSDTEIYKRLLPLYFPRDEHEEEVAISKLPA 270

  Fly   252 DIGGEFGEPQHPDPDRQIRIIRN--PQHSVHMRHHLADDDSDVSPHDMEGNSSDLEYGARDMNGL 314
            |:|.|.||....:...:|:.:.|  |..|.              |..:|..|:||....|:.|
plant   271 DVGDENGETVIDERKIRIQALPNKPPPRSF--------------PTPLERPSTDLTLLRRNSN-- 319

  Fly   315 SLNSYSSGLQAQLQRDLD----RQHLLSDRPRTGV-YENVISEG------VEGIEHQERYERLLR 368
            .|:||.......|.:|.|    .|...:.:.::|. :..::..|      :...|....:.|.|.
plant   320 HLDSYLDPAFMSLIKDPDERRKEQWEKTAQAQSGFNFVKLLGFGDLGGPPLSAAEEYSLHSRYLA 384

  Fly   369 RAQVEDLTEVSGIGCLYQSGVDRLGRPVIVFCGKWFPAQNIDLEKALLYLIKLLDPIVKGDYVIS 433
            :|...:|:|::.:..:|:.|||..|.||:|..|..|..:.:|||:.:||:||..:|:::..|.|.
plant   385 KANSINLSEIAEMKIVYRGGVDTEGHPVMVVVGAHFLLRCLDLERFVLYVIKEFEPVIQKPYSIV 449

  Fly   434 YFHTLTSTNNYPSLHWLREVYSVLPYKYKKNLKAFYIVHPTFWTKMMTWWFTTFMAPAIKAKVHS 498
            |||:..|....|.|.|::.:..:|..|:::||:|.|::||||..|........|:...:..||..
plant   450 YFHSAASLQVQPDLGWMKRLEQILGRKHQRNLQAIYVLHPTFHLKATILTMQFFVDNVVWKKVVY 514

  Fly   499 LPGVEHLYSAITKDQLEIPAYITEYDMATNG 529
            ...:..|:..:.::||.||.::.::|:..||
plant   515 ADRLLQLFKYVPREQLTIPDFVFQHDLEVNG 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gdap2	NP_724597.1	YmdB	67..234	CDD:225021	69/169 (41%)
		Macro_GDAP2_like	67..207	CDD:239233	60/139 (43%)
		CRAL_TRIO_2	393..518	CDD:290435	41/124 (33%)
AT1G69340	NP_001323191.1	Macro_GDAP2-like	85..253	CDD:394876	69/169 (41%)
AT1G69340	NP_001323191.1	CRAL_TRIO_2	409..542	CDD:404584	43/132 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	89	1.000	Domainoid score	I2680
eggNOG	1	0.900	-	-		E1_COG2110
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7728
Inparanoid	1	1.050	256	1.000	Inparanoid score	I997
OMA	1	1.010	-	-		QHG55405
OrthoDB	1	1.010	-	-		D937161at2759
OrthoFinder	1	1.000	-	-		FOG0007360
OrthoInspector	1	1.000	-	-		oto2898
orthoMCL	1	0.900	-	-		OOG6_105245
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5478
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.780