Protein Alignment Gdap2 and Macrod2

DIOPT Version :10

• Sequence 1: NP_724597.1
• Gene: Gdap2 / 59173
• FlyBaseID: FBgn0042135
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001393313.1
• Gene: Macrod2 / 72899
• MGIID: 1920149
• Length: 476
• Species: Mus musculus
• Alignment Length: 305
• Identity: 89/305 - (29%)
• Similarity: 135/305 - (44%)
• Gaps: 33/305 - (10%)

  Fly    23 VKLDNLATWGGSQKTDTRLPITDYSNLGGPRHNRSPFP-LCKDVNNRFVIWDGDMTTLEVDAITN 86
            |.|..:.:|....|:..:          ....|....| :.|.::.:..::.||:|.||||||.|
Mouse    35 VSLSTILSWKEEMKSKGQ----------NDEENTQEAPQMKKSLSEKVSLYRGDITLLEVDAIVN 89

  Fly    87 TSDETLTESNSISERIFAVAGNQLREELSTTVKECRTGDVRITRGYNLPAKYVLHTVAPAYREKF 151
            .::.:|.....:...|...||..|..| ...:..|.||..:||.||:||||||:|||.|..|...
Mouse    90 AANASLLGGGGVDGCIHRAAGPCLLAE-CRNLNGCETGHAKITCGYDLPAKYVIHTVGPIARGHI 153

  Fly   152 KTAAENTLHCCYRNVLCKAKELNLHTIALCNISAHQKSFPADVAAHIALRTIRRYLDKCTLQV-- 214
            ..:.:..|..||::.|...||.||.::|...||.....||.:.||.|||.||:.:|.|...:|
Mouse   154 NGSHKEDLANCYQSSLKLVKENNLRSVAFPCISTGIYGFPNEPAAVIALGTIKEWLAKNHQEVDR 218

  Fly   215 VILCVGSSERGTYEVLAPLY-------FPRDQLEERSALWQLPKDIGGEFGEPQHPDPDRQIRII 272
            :|.||      ..||...:|       ||.|...|.:.. .:.:|..|.  ||:...|..:....
Mouse   219 IIFCV------FLEVDFKIYKKKMNEFFPVDDNNEGTDA-DMKEDSEGP--EPKGLSPPHKKSKA 274

  Fly   273 RNPQHSVHMRHHLADDDSDVSPHDMEGNSSD---LEYGARDMNGL 314
            :.|:.|.......:..:...:..:|||.|.:   |.:..|::.||
Mouse   275 KKPESSKDSSEDESGPEEKQTAEEMEGQSQEAGGLRFLLRNLLGL 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gdap2	NP_724597.1	Macro_GDAP2-like	67..234	CDD:394876	62/168 (37%)
		CRAL_TRIO_2	393..524	CDD:463965
Macrod2	NP_001393313.1	Macro_OAADPr_deacetylase	71..237	CDD:438955	63/172 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	241..306		14/67 (21%)