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Protein Alignment Gdap2 and PARP14

DIOPT Version :9

Sequence 1:	NP_724597.1	Gene:	Gdap2 / 59173	FlyBaseID:	FBgn0042135	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_060024.2	Gene:	PARP14 / 54625	HGNCID:	29232	Length:	1801	Species:	Homo sapiens

Alignment Length:	381	Identity:	80/381 - (20%)
Similarity:	155/381 - (40%)	Gaps:	67/381 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 EVDAITNTSDETLTESNS-ISERIFAVAGNQLREELSTTVK--ECRTGDVRITRGYNLPAKYVLH 141
            :.|.:.|:....|..|.. :|:.:...||.:|:|||.|..:  ....|.|..|..:||..:||||
Human  1027 KTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMGTVLKTSSWNLDCRYVLH 1091

  Fly   142 TVAPAYREKFKTAAENTLHCCYRNVLCKAKELNLHTIALCNISAHQKSFPADVAAHIALRTIRRY 206
            .|||.:|.. .|::...:....|..:...:.|:|.:||...|......||.::.|.:.:..:.::
Human  1092 VVAPEWRNG-STSSLKIMEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKF 1155

  Fly   207 LDK---CTLQVVILCVGSSERGTYEVLAPLYFPRDQLEERS----ALWQLP--KDIGGEFGEPQH 262
            ..|   .|||.|...:..|:....:..:      |:...|:    ...::|  ||..|.:|....
Human  1156 SSKNQLKTLQEVHFLLHPSDHENIQAFS------DEFARRANGNLVSDKIPKAKDTQGFYGTVSS 1214

  Fly   263 PDPD-RQIRIIRNPQHSVHMRHHLAD---DDSDVSPHDMEGNSSDLEYGARDMNGLSLNSYSSGL 323
            ||.. .:::|     .|:..:....|   :::||..:. ..||.:|:.|.           |..:
Human  1215 PDSGVYEMKI-----GSIIFQVASGDITKEEADVIVNS-TSNSFNLKAGV-----------SKAI 1262

  Fly   324 QAQLQRDLDRQHLLSDRPRTGVY----------ENVISEGVEGIEHQERYERLLRRAQVEDLTEV 378
            .....::::|:.....:.|...|          :|:| ..:.|.:.:.....:|:..:.::.:.:
Human  1263 LECAGQNVERECSQQAQQRKNDYIITGGGFLRCKNII-HVIGGNDVKSSVSSVLQECEKKNYSSI 1326

  Fly   379 SGIGCLYQSGV-------DRLGRPVI----VFCGKWFPAQNIDLEKALLYLIKLLD 423
                ||...|.       |::...:|    .|..|. .||::...|.:::|.::||
Human  1327 ----CLPAIGTGNAKQHPDKVAEAIIDAIEDFVQKG-SAQSVKKVKVVIFLPQVLD 1377

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.