DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gdap2 and macrod1

DIOPT Version :9

Sequence 1:	NP_724597.1	Gene:	Gdap2 / 59173	FlyBaseID:	FBgn0042135	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001004573.2	Gene:	macrod1 / 447834	ZFINID:	ZDB-GENE-040912-100	Length:	327	Species:	Danio rerio

Alignment Length:	203	Identity:	74/203 - (36%)
Similarity:	110/203 - (54%)	Gaps:	8/203 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 LPITDYSNLGGPRHNRSPFPLC---KDVNNRFVIWDGDMTTLEVDAITNTSDETLTESNSISERI 102
            :|:.|.. :..|..:.|..|.|   :::|.:..::.||:|.||:||:.|.:::||.....:...|
Zfish   119 IPLEDVP-VWSPSGDSSCKPRCEVNEELNMKVSLFGGDITKLEIDAVANAANKTLLGGGGVDGAI 182

  Fly   103 FAVAGNQLREELSTTVKECRTGDVRITRGYNLPAKYVLHTVAPAYREKFKTAAENTLHCCYRNVL 167
            ...||..||:|.: |:..|.||:.:||..|.|||:||:|||.|...:......|..|..||.|.|
Zfish   183 HRGAGPLLRKECA-TLNGCETGEAKITGAYGLPARYVIHTVGPIVHDSVGEREEEALRNCYYNCL 246

  Fly   168 CKAKELNLHTIALCNISAHQKSFPADVAAHIALRTIRRYLDKC--TLQVVILCVG-SSERGTYEV 229
            ..|.:.:|.|:|...||.....:|.|.|..:||:|:|.||::.  .|..||.||. .|::..||.
Zfish   247 HTATKHHLRTVAFPCISTGVYGYPPDQAVEVALKTVRDYLEQNPEKLDRVIFCVFLKSDKQLYEN 311

  Fly   230 LAPLYFPR 237
            |.|.||||
Zfish   312 LLPAYFPR 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gdap2	NP_724597.1	YmdB	67..234	CDD:225021	63/169 (37%)
		Macro_GDAP2_like	67..207	CDD:239233	51/139 (37%)
		CRAL_TRIO_2	393..518	CDD:290435
macrod1	NP_001004573.2	Macro_Appr_pase_like	148..314	CDD:239236	62/166 (37%)
macrod1	NP_001004573.2	YmdB	154..313	CDD:225021	61/159 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2110
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D564346at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820