DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gdap2 and Parp14

DIOPT Version :9

Sequence 1:NP_724597.1 Gene:Gdap2 / 59173 FlyBaseID:FBgn0042135 Length:540 Species:Drosophila melanogaster
Sequence 2:NP_001178588.1 Gene:Parp14 / 303903 RGDID:1310490 Length:1787 Species:Rattus norvegicus


Alignment Length:487 Identity:95/487 - (19%)
Similarity:181/487 - (37%) Gaps:129/487 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    70 VIWDGDMTTLEVDAITNTSDETLTESNSISERIFAVAGNQLREELSTTVKE---CRTGDVRITRG 131
            ::.:||::...||.:.|.::|:|...:.::..:...||..|:.|....||:   ...|:..|::.
  Rat   796 IVHEGDLSLFPVDVVVNAANESLKHIDGLAGTLSKAAGPSLQAECDLIVKKGGMVPPGNAVISKA 860

  Fly   132 YNLPAKYVLHTVAPAYREKFKTAAENTLHCCYRNVLCKAKELNLHTIALCNISAHQKSFPAD--- 193
            ..||.:||:|.|.|.::........|.|....:..|..|:|....:||:..||:....||.|   
  Rat   861 GKLPCRYVIHAVGPRWKGDKVLECVNLLKKAVKQSLTLAEEYKCQSIAIPAISSGIFDFPLDLCV 925

  Fly   194 --VAAHIALRTIRRYLDKCTLQVVILCVGSSERGTY-EVLAPLYFPRDQLEERSALWQLPKDIGG 255
              :|:.|.....::.......::.::.|.:.....: |.:...|  ||.|...|....:|.   |
  Rat   926 ASIASAIKDNVQQKQNTHSVKKIYLVDVSAKVAKAFAEAVKTTY--RDILSPASVKALVPP---G 985

  Fly   256 EFGEPQHPDPDRQIRIIRNPQHSVHMRHHLADDDSDVSPHDMEGNSSDLEYGARDMNGLSL-NSY 319
            :.       |.:|.:::                   |||..:  |...:|.|.::....:: ||.
  Rat   986 KM-------PQKQGKLL-------------------VSPEGL--NIRLIEEGVQNAEAHAIVNSV 1022

  Fly   320 SSGLQAQLQRDLDRQHLLSDRPRTGVYENVISEGVEGIEHQERYERLLRRAQVEDLTEVSGIGCL 384
            ||.|            :|:..|.:..:  :.|.|      .|..|.|.:..|...::    :|.:
  Rat  1023 SSDL------------ILNKGPLSQAF--LESAG------PELQEELTKAGQGVSVS----VGTV 1063

  Fly   385 YQ-SGVDRLGRPVI-VFCGKWFPAQNIDLEKALLYLIKLLDPIVKGDYV----------ISYFHT 437
            .| ||.:...|.:. |....| .:.|.:      :.:|::..|:: |.:          |::...
  Rat  1064 LQTSGCNLNSRSIFHVVTPPW-KSNNSE------WSLKIMKNIIR-DCLRTTEDLSLQSIAFPAI 1120

  Fly   438 LTSTNNYPSLHWLREVYS-VLPYKYKKNLKAF----YIVHPTFWTKMMTWWFTTFMAPAIKAKVH 497
            .|....:|...:.:.:.| ||.:..:..||..    :::||                        
  Rat  1121 GTGNLGFPKPEFAKLIISEVLKFSSRNQLKTLQEVQFLLHP------------------------ 1161

  Fly   498 SLPGVEHLYSAITKDQLEIPAYITEYDMATNG 529
                         ||...|.|::.|:|..:||
  Rat  1162 -------------KDHENIQAFLDEFDKRSNG 1180

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gdap2NP_724597.1 YmdB 67..234 CDD:225021 38/172 (22%)
Macro_GDAP2_like 67..207 CDD:239233 36/144 (25%)
CRAL_TRIO_2 393..518 CDD:290435 20/140 (14%)
Parp14NP_001178588.1 RRM1_PAR14 6..88 CDD:240746
RRM2_PAR14 223..297 CDD:240987
YmdB 792..971 CDD:225021 39/176 (22%)
Macro_Af1521_BAL_like 792..967 CDD:239235 38/170 (22%)
Macro 1001..1143 CDD:294024 33/175 (19%)
Macro 1216..1340 CDD:294024
W2 <1327..>1368 CDD:302589
PARP 1613..1786 CDD:279038
TCCD_inducible_PARP_like 1665..1785 CDD:238719
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2110
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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