DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gdap2 and Macroh2a1

DIOPT Version :9

Sequence 1:	NP_724597.1	Gene:	Gdap2 / 59173	FlyBaseID:	FBgn0042135	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_036145.1	Gene:	Macroh2a1 / 26914	MGIID:	1349392	Length:	372	Species:	Mus musculus

Alignment Length:	160	Identity:	39/160 - (24%)
Similarity:	70/160 - (43%)	Gaps:	16/160 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 DMTTLEVDAITNTSDETLTESNSISERIFAVAGNQLRE---ELSTTVKECRTGDVRITRGYNLPA 136
            ::...||:||.|.::..:...:.:...:....|.:..|   ||.............|:.|:.|||
Mouse   206 NLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAISAGHGLPA 270

  Fly   137 KYVLHTVAPAY-REKFKTAAENTLHCCYRNVLCKAKELNLHTIALCNISAHQKSFPADVAAHIAL 200
            |:|:|..:|.: .:|.:...|.|:    :|.|..|.:..|.:||..:|.:.:..||...||.:.|
Mouse   271 KFVIHCNSPVWGADKCEELLEKTV----KNCLALADDRKLKSIAFPSIGSGRNGFPKQTAAQLIL 331

  Fly   201 RTIRRYLDKCTLQVVILCVGSSERGTYEVL 230
            :.|..|.        :..:.||.:..|.:|
Mouse   332 KAISSYF--------VSTMSSSIKTVYFML 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gdap2	NP_724597.1	YmdB	67..234	CDD:225021	39/160 (24%)
		Macro_GDAP2_like	67..207	CDD:239233	34/135 (25%)
		CRAL_TRIO_2	393..518	CDD:290435
Macroh2a1	NP_036145.1	H2A	5..117	CDD:238029
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	128..180
		Macro_H2A_like	178..364	CDD:239232	39/160 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2110
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810