Protein Alignment Gdap2 and Gdap2

DIOPT Version :10

• Sequence 1: NP_724597.1
• Gene: Gdap2 / 59173
• FlyBaseID: FBgn0042135
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_034399.1
• Gene: Gdap2 / 14547
• MGIID: 1338001
• Length: 498
• Species: Mus musculus
• Alignment Length: 523
• Identity: 204/523 - (39%)
• Similarity: 315/523 - (60%)
• Gaps: 45/523 - (8%)

  Fly    23 VKLDNLATWGGSQKTDTRLPITDYSNLGGPRH----NRSPFPLCKDVNNRFVIWDGDMTTLEVDA 83
            |.:|.|.:||.|.:.:     .|.::......    :||||...:|||.:.|:|.||:..|...|
Mouse    11 VDVDTLLSWGDSYEDE-----VDCADSTAEAFQEDASRSPFVYSRDVNGKVVLWKGDVALLNCTA 70

  Fly    84 ITNTSDETLTESNSISERIFAVAGNQLREELSTTVKECRTGDVRITRGYNLPAKYVLHTVAPAYR 148
            |.|||:|:||:.|.:||.||.:||..|:|:|. .:|.||||:.::|:|:||.|::::|||.|.|:
Mouse    71 IVNTSNESLTDKNPVSESIFMLAGPDLKEDLQ-KLKGCRTGEAKLTKGFNLAARFIIHTVGPKYK 134

  Fly   149 EKFKTAAENTLHCCYRNVLCKAKELNLHTIALCNISAHQKSFPADVAAHIALRTIRRYLD--KCT 211
            .:::||||::|:.||||||..|||.::.::..|.|::.::.:|.:.|.||||||:||:|:  ...
Mouse   135 SRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGEN 199

  Fly   212 LQVVILCVGSSERGTYEVLAPLYFPRDQLEERSALWQLPKDIGGEFGEPQHPDPDRQIRIIRNPQ 276
            ::.|:..|...|..||:.|.||||||...||..:|..||.|||...|||  ..|:|||||...|.
Mouse   200 IEKVVFAVSELEEATYQKLLPLYFPRSLKEEIRSLPYLPADIGNAEGEP--VVPERQIRISEKPG 262

  Fly   277 HSVHMRHHLADDDSDVSPHDMEGNSSDLEYGARDMNGLSLNSYSSGLQAQLQRDLDRQHLLSDRP 341
                     |.:|::....| ||...||.:         :.|::.   |:::.|:|:|..|
Mouse   263 ---------ASEDNEEEDED-EGLGVDLSF---------IGSHAF---ARMEGDIDKQRKL---- 301

  Fly   342 RTGVYENVISEGVEGIEHQERYERLLRRAQVEDLTEVSGIGCLYQSGVDRLGRPVIVFCGKWFPA 406
               :.:..:||.....:||..|.|.|.:|:.|||::::.:..|||:|||..||.|:|..|:..|.
Mouse   302 ---ILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPV 363

  Fly   407 QNIDLEKALLYLIKLLDPIVKGDYVISYFHTLTSTNNYPSLHWLREVYSVLPYKYKKNLKAFYIV 471
            ..||::|||||.|.::|.|...:||:.|||||||..|:....:|:::|.|:..|||:||||.|.|
Mouse   364 TLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSDYNHLDSDFLKKLYDVVDIKYKRNLKAVYFV 428

  Fly   472 HPTFWTKMMTWWFTTFMAPAIKAKVHSLPGVEHLYSAITKDQLEIPAYITEYDMATNGLHY--FN 534
            ||||.:|:.||:||||....:|.|:|.:..::.|:|||:.:|::.|.::.|||...||.::  :.
Mouse   429 HPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLQQLFSAISPEQIDFPPFVLEYDARENGPYFASYP 493

  Fly   535 PVP 537
            |.|
Mouse   494 PSP 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gdap2	NP_724597.1	Macro_GDAP2-like	67..234	CDD:394876	72/168 (43%)
		CRAL_TRIO_2	393..524	CDD:463965	59/130 (45%)
Gdap2	NP_034399.1	Macro_GDAP2-like	55..222	CDD:394876	72/168 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	248..275		8/26 (31%)
		CRAL_TRIO_2	350..481	CDD:463965	62/130 (48%)