DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18810 and Zdhhc4

DIOPT Version :9

Sequence 1:	NP_652670.2	Gene:	CG18810 / 59171	FlyBaseID:	FBgn0042133	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_082655.1	Gene:	Zdhhc4 / 72881	MGIID:	1920131	Length:	343	Species:	Mus musculus

Alignment Length:	231	Identity:	62/231 - (26%)
Similarity:	95/231 - (41%)	Gaps:	47/231 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 QFLFLFILCGLPAIYYVLMEI--ILPELSDYWSPGYVFQ----LLLGLFLFSNVMSNYVMCILVD 75
            :|...::|  ||   |||:.:  :...|:...:||.:.:    .||.::.|.:||
Mouse    95 EFSLPYLL--LP---YVLLSVNLVFFTLTCAANPGTITKANESFLLQVYKFDDVM---------- 144

  Fly    76 PSIDPKLMKNQLVRGQHSEDWHECDKCGILAPPRSRHCRKCGVCVLMRDHHCFFTGCCIGHENYR 140
                  ..||.           .|..|.:..|.||:|||.|..||...||||.:...|||..|.|
Mouse   145 ------FPKNS-----------RCPTCDLRKPARSKHCRLCDRCVHRFDHHCVWVNNCIGAWNTR 192

  Fly   141 YFFYFLIYFFLSCMISLTSSSIFI--YVLHGGRYQLFMLTHPAPNSAYFNSLIIRIIYFKLPDI- 202
            ||..:|:....|.....|.::.|:  .|.....||...|.......|.....:|:.::...|.|
Mouse   193 YFLIYLLTLTASAATIATVTAAFLLRLVTVSDLYQETYLDDVGHFQAVDTVFLIQHLFLAFPRIV 257

  Fly   203 YELVFTLVFVLLWIG-VCVATYVA-----YDQWSRG 232
            :.|.|.:|..:|..| :|.|.|:|     .::|.:|
Mouse   258 FLLGFVIVLSMLLAGYLCFALYLAATNQTTNEWYKG 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18810	NP_652670.2	zf-DHHC	92..>138	CDD:303066	18/45 (40%)
Zdhhc4	NP_082655.1	DHHC	151..292	CDD:396215	44/140 (31%)
Zdhhc4	NP_082655.1	Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9NPG8	340..343
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810