DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18810 and Zdhhc6

DIOPT Version :9

Sequence 1:	NP_652670.2	Gene:	CG18810 / 59171	FlyBaseID:	FBgn0042133	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_001028745.1	Gene:	Zdhhc6 / 66980	MGIID:	1914230	Length:	413	Species:	Mus musculus

Alignment Length:	266	Identity:	70/266 - (26%)
Similarity:	107/266 - (40%)	Gaps:	53/266 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 YW----SPGYV-FQLLLGLFLFSNVMSNYVMCILVDPSIDPKLMKNQLVRGQHSEDWHECDKCGI 104
            ||    :.|.| |.:|:...:.  ::.||...:...|...|:..|.:  :.|.|.....|..|..
Mouse    46 YWPLHTTGGSVNFIMLINWTVM--ILYNYFNAMFAGPGFVPRGWKPE--KSQDSMYLQYCKVCQA 106

  Fly   105 LAPPRSRHCRKCGVCVLMRDHHCFFTGCCIGHENYRYFFYFLIYFFLSCMISLTSSSIFIYVLHG 169
            ...|||.|||||..||:..||||.:...|.||:|:..|..||:...|.|     :.:.||:|:
Mouse   107 YKAPRSHHCRKCNRCVMKMDHHCPWINNCCGHQNHASFTLFLLLAPLGC-----THAAFIFVM-- 164

  Fly   170 GRY-QLFMLTHPAPNSAYFNSLIIR-----IIYFKLPDIYELVFTLVFVL-----------LWIG 217
            ..| ||:.......|:...:....|     |:.|.|......:|.|...|           :.|.
Mouse   165 TMYTQLYNRLSFGWNTVKIDMSAARRDPPPIVPFGLAAFAATLFALGLALGTTIAVGMLFFIQIK 229

  Fly   218 VCVATYVAYDQWSR-------GYFCYDFELQNIPFDRKLR-RNFKTFLGRRMKWTWISGFVPSQL 274
            :.:....:.:.|..       .|:..| |:...|:|...: :|||      ..:|| || ||
Mouse   230 IILRNKTSIESWIEEKAKDRIQYYQLD-EVFIFPYDMGSKWKNFK------QVFTW-SG-VP--- 282

  Fly   275 DHDGFD 280
            :.||.:
Mouse   283 EGDGLE 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18810	NP_652670.2	zf-DHHC	92..>138	CDD:303066	20/45 (44%)
Zdhhc6	NP_001028745.1	DHHC	95..241	CDD:366691	41/152 (27%)
		SH3_2	317..396	CDD:369452
		Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9H6R6	410..413
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810